87307-83-3Relevant articles and documents
Synthesis of enantiopure 10-nornaltrexones in the search for toll-like receptor 4 antagonists and opioid ligands
Selfridge, Brandon R.,Deschamps, Jeffrey R.,Jacobson, Arthur E.,Rice, Kenner C.
, p. 5007 - 5018 (2014/06/23)
10-Nornaltrexones (3-(cyclopropylmethyl)-4a,9-dihydroxy-2,3,4,4a,5,6- hexahydro-1H-benzofuro[3,2-e]isoquinolin-7(7aH)-one, 1) have been underexploited in the search for better opioid ligands, and their enantiomers have been unexplored. The synthesis of tr