881674-06-2

Basic information

• Product Name: 1H-Pyrrole-3-carboxylic acid, 5-(2-fluorophenyl)-, ethyl ester
• Synonyms: 1H-Pyrrole-3-carboxylic acid, 5-(2-fluorophenyl)-, ethyl ester;5-(2-Fluorophenyl)-1H-pyrrole-3-carboxylic acid ethyl ester;Ethyl 5-(2-fluorophenyl)-1H-pyrrole-3-carboxylate
• CAS NO: 881674-06-2
• Molecular Formula: C₁₃H₁₂FNO₂
• Molecular Weight: 233.2382832
• Mol File: 881674-06-2.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 424.7±35.0 °C(Predicted)
• Appearance: /
• Density: 1.217±0.06 g/cm3 (20 ºC 760 Torr)
• PKA: 14.68±0.50(Predicted)
• CAS DataBase Reference: 1H-Pyrrole-3-carboxylic acid, 5-(2-fluorophenyl)-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrole-3-carboxylic acid, 5-(2-fluorophenyl)-, ethyl ester(881674-06-2)
• EPA Substance Registry System: 1H-Pyrrole-3-carboxylic acid, 5-(2-fluorophenyl)-, ethyl ester(881674-06-2)

Safety Data

• Hazardous Substances Data: 881674-06-2(Hazardous Substances Data)

Usage

General Description

1H-Pyrrole-3-carboxylic acid, 5-(2-fluorophenyl)-, ethyl ester is a chemical compound that belongs to the class of pyrrole derivatives. It is an ethyl ester derivative of 1H-Pyrrole-3-carboxylic acid, which is a heterocyclic compound with a pyrrole ring. The addition of an ethyl ester group and a 2-fluorophenyl substituent further modifies the chemical properties of the compound. This chemical may have applications in the field of pharmaceuticals or organic synthesis due to its potential for forming new chemical entities with desired properties. Its structure and properties make it a potential candidate for further research and development in various industries.

Upstream product

• 881674-01-7 ethyl 2-chloro-5-(2-fluorophenyl)-1H-pyrrole-3-carboxylate 
• 445-27-2 2'-Fluoroacetophenone 
• 105-56-6 ethyl 2-cyanoacetate 
• 655-15-2 2-bromo-2'-fluoroacetophenone 
• 881673-98-9 ethyl 2-cyano-4-(2-fluorophenyl)-4-oxobutanoate 

Downstream Products

• 2098974-13-9 1-[5-(2-fluorophenyl)-1-(pyridine-3-sulfonyl)-1H-pyrrole-3-yl]-N-methylmethylamine fumaric acid salt 
• 881681-00-1 1-(5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-yl)-N-methylmethanamine 
• 881674-56-2 5-(2-fluorophenyl)-1H-pyrrole-3-carboxaldehyde 
• 881677-11-8 5‐(2-fluorophenyl)‐1‐(pyridine-3-sulfonyl)-1H-pyrrole-3-carbaldehyde 
• 881677-02-7 5-(2-fluorophenyl)-1-{[3-(methylsulfonyl)phenyl]sulfonyl}-1H-pyrrole-3-carbaldehyde 
• 881677-04-9 1-{[3-(ethylsulfonyl)phenyl]sulfonyl}-5-(2-fluorophenyl)-1H-pyrrole-3-carbaldehyde 
• 881677-06-1 2-{[2-(2-fluorophenyl)-4-formyl-1H-pyrrol-1-yl]sulfonyl}benzonitrile 
• 881677-08-3 4-{[2-(2-fluorophenyl)-4-formyl-1H-pyrrol-1-yl]sulfonyl}benzonitrile 
• 881677-09-4 5-(2-fluorophenyl)-1-[(2-fluorophenyl)sulfonyl]-1H-pyrrole-3-carbaldehyde 
• 1883595-39-8 C₁₇H₁₄FN₃O₃S 
• 1883595-37-6 5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carboxylic acid 

Relevant articles and documents

Identification of a novel fluoropyrrole derivative as a potassium-competitive acid blocker with long duration of action

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Proton pump inhibitors

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Acid secretion inhibitor

The present invention provides a compound having a superior acid secretion inhibitory effect and showing an antiulcer activity and the like. The present invention provides a compound represented by the formula (I) wherein R1 is a nitrogen-containing monocyclic heterocyclic group optionally condensed with a benzene ring or a heterocycle, the nitrogen-containing monocyclic heterocyclic group optionally condensed with a benzene ring or a heterocycle optionally has substituent(s), R2 is an optionally substituted C6-14 aryl group, an optionally substituted thienyl group or an optionally substituted pyridyl group, R3 and R4 are each a hydrogen atom, or one of R3 and R4 is a hydrogen atom and the other is an optionally substituted lower alkyl group, an acyl group, a halogen atom, a cyano group or a nitro group, and R5 is an alkyl group or a salt thereof.