884504-23-8 Usage
General Description
2-METHYL-5-FLUOROBENZOYLACETONITRILE is a chemical compound with the formula C10H8FN. It is a white to off-white solid that is used in the synthesis of pharmaceuticals and agrochemicals. The compound is also used as an intermediate in the production of various organic compounds. Its molecular structure consists of a benzoyl group attached to a nitrile group, with a fluorine and a methyl group attached to the benzene ring. It is important to handle this compound with care and use proper safety measures, as it may be harmful if ingested, inhaled, or comes into contact with the skin.
Check Digit Verification of cas no
The CAS Registry Mumber 884504-23-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,4,5,0 and 4 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 884504-23:
(8*8)+(7*8)+(6*4)+(5*5)+(4*0)+(3*4)+(2*2)+(1*3)=188
188 % 10 = 8
So 884504-23-8 is a valid CAS Registry Number.
InChI:InChI=1/C10H8FNO/c1-7-2-3-8(11)6-9(7)10(13)4-5-12/h2-3,6H,4H2,1H3
884504-23-8Relevant articles and documents
Fungal-Selective Resorcylate Aminopyrazole Hsp90 Inhibitors: Optimization of Whole-Cell Anticryptococcal Activity and Insights into the Structural Origins of Cryptococcal Selectivity
Marcyk, Paul T.,Leblanc, Emmanuelle V.,Kuntz, Douglas A.,Xue, Alice,Ortiz, Francisco,Trilles, Richard,Bengtson, Stephen,Kenney, Tristan M. G.,Huang, David S.,Robbins, Nicole,Williams, Noelle S.,Krysan, Damian J.,Privé, Gilbert G.,Whitesell, Luke,Cowen, Leah E.,Brown, Lauren E.
, p. 1139 - 1169 (2021/02/01)
The essential eukaryotic chaperone Hsp90 regulates the form and function of diverse client proteins, many of which govern thermotolerance, virulence, and drug resistance in fungal species. However, use of Hsp90 inhibitors as antifungal therapeutics has be