88958-64-9

Basic information

• Product Name: (4S)-4-hydroxy-4-(4-nitrophenyl)-butan-2-one
• Synonyms: (4S)-4-hydroxy-4-(4-nitrophenyl)-butan-2-one
• CAS NO: 88958-64-9
• Molecular Weight: 209.202
• Mol File: 88958-64-9.mol
• Article Data: 265

Chemical Properties

• CAS DataBase Reference: (4S)-4-hydroxy-4-(4-nitrophenyl)-butan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (4S)-4-hydroxy-4-(4-nitrophenyl)-butan-2-one(88958-64-9)
• EPA Substance Registry System: (4S)-4-hydroxy-4-(4-nitrophenyl)-butan-2-one(88958-64-9)

Safety Data

• Hazardous Substances Data: 88958-64-9(Hazardous Substances Data)

Upstream product

• 946-49-6 4-(p-nitrophenyl)-3-butene-2-one 
• 555-16-8 4-nitrobenzaldehdye 
• 67-64-1 acetone 
• 104-94-9 4-methoxy-aniline 
• 2033-24-1 cycl-isopropylidene malonate 
• 123-42-2 4-Hydroxy-4-methyl-2-pentanone 
• 42856-71-3 (S)-2-methylpyrrolidine-2-carboxylic acid 
• 552-89-6 2-nitro-benzaldehyde 
• 141-97-9 ethyl acetoacetate 
• 105-45-3 acetoacetic acid methyl ester 
• 25746-83-2 (2S)-N-phenylpyrrolidine-2-carboxamide 
• 108-22-5 Isopropenyl acetate 
• 88958-64-9 1-(4-nitrophenyl)-1-hydroxy-3-butanone 
• 147-85-3 L-proline 

Downstream Products

• 946-49-6 (E)-4-(4-nitrophenyl)-3-buten-2-one 
• 555-16-8 4-nitrobenzaldehdye 
• 67-64-1 acetone 
• 946-49-6 4-(p-nitrophenyl)-3-butene-2-one 
• 62-23-7 4-nitro-benzoic acid 
• 337373-49-6 4-hydroxy-4-(4'-nitrophenyl)-butan-2-one ethylene acetal 
• 673492-37-0 (4RS)-4-(tert-butyldimethylsilyloxy)-4-(4-nitrophenyl)butan-2-one 
• 264224-65-9 (4R)-4-hydroxy-4-(4-nitrophenyl)-butan-2-one 
• 791589-81-6 1-(4-nitrophenyl)-3-oxobutyl acetate 
• 1356828-01-7 (1R,3R)-1-(4-nitrophenyl)-1,3-butanediol 
• 1356828-06-2 (1S,3R)-1-(4-nitrophenyl)-1,3-butanediol 
• 1356828-04-0 (1S,3S)-1-(4-nitrophenyl)-1,3-butanediol 
• 62596-10-5 3-methyl-5-(4-nitrophenyl)cyclohex-2-enone 
• 1204698-94-1 (1R,3S)-1-(4-nitrophenyl)-1,3-butanediol 

Relevant articles and documents

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Chiral imidazolium L-prolinate salts, providing a complex network of supramolecular interaction in a chiral environment, have been studied as synzymatic catalytic systems. They are demonstrated to be green and efficient chiral organocatalysts for direct asymmetric aldol reactions at room temperature. The corresponding aldol products were obtained with moderate to good enantioselectivities. The influence of the presence of chirality in both the imidazolium cation and the prolinate anion on the transfer of chirality from the organocatalyst to the aldol product has been studied. Moreover, interesting match/mismatch situations have been observed regarding configuration of chirality of the two components through the analysis of results for organocatalysts derived from both enantiomers of prolinate (R/S) and the trans/cis isomers for the chiral fragment of the cation. This is associated with differences in the corresponding reaction rates but also to the different tendencies for the formation of aggregates, as evidenced by nonlinear effects studies (NLE). Excellent activities, selectivities, and enantioselectivities could be achieved by an appropriate selection of the structural elements at the cation and anion.