90247-08-8

Basic information

• Product Name: 8-chloro-3-(2-fluorophenyl)-5,6-dihydrofuro[3,2-f][1,2]benzoxazole-6-carboxylic acid
• Synonyms: A53385;A-53385;A 53385;A 56234
• CAS NO: 90247-08-8
• Molecular Formula: C₁₆H₉ClFNO₄
• Molecular Weight: 333.6984
• Mol File: 90247-08-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 570.5°C at 760 mmHg
• Flash Point: 298.8°C
• Density: 1.563g/cm³
• Vapor Pressure: 7.42E-14mmHg at 25°C
• Refractive Index: 1.664
• CAS DataBase Reference: 8-chloro-3-(2-fluorophenyl)-5,6-dihydrofuro[3,2-f][1,2]benzoxazole-6-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 8-chloro-3-(2-fluorophenyl)-5,6-dihydrofuro[3,2-f][1,2]benzoxazole-6-carboxylic acid(90247-08-8)
• EPA Substance Registry System: 8-chloro-3-(2-fluorophenyl)-5,6-dihydrofuro[3,2-f][1,2]benzoxazole-6-carboxylic acid(90247-08-8)

Safety Data

• Hazardous Substances Data: 90247-08-8(Hazardous Substances Data)

Upstream product

• 90246-88-1 ethyl (E)-7-chloro-2,3-dihydro-5-(o-fluorobenzoyl)-6-hydroxybenzofuran-2-carboxylate oxime 
• 90246-78-9 ethyl 7-chloro-2,3-dihydro-5-(o-fluorobenzoyl)-6-hydroxybenzofuran-2-carboxylate 
• 90246-71-2 diethyl 7-chloro-2,3-dihydro-3-hydroxy-6-methoxybenzofuran-2,2-dicarboxylate 
• 90246-73-4 diethyl 7-chloro-2,3-dihydro-6-methoxybenzofuran-2,2-dicarboxylate 
• 72482-15-6 3-chloro-2-hydroxy-4-methoxybenzaldehyde 
• 72482-14-5 3-chloro-2,4-dimethoxybenzaldehyde 
• 7051-15-2 2-chlororesorcinol dimethyl ether 
• 90246-98-3 ethyl 8-chloro-5,6-dihydro-3-(o-fluorophenyl)furo[3,2-f]-1,2-benzisoxazole-6-carboxylate 
• 90246-99-4 ethyl (E)-7-chloro-2,3-dihydro-5-(o-fluorobenzoyl)-6-hydroxybenzofuran-2-carboxylate O-acetyloxime 
• 90246-72-3 ethyl 7-chloro-2,3-dihydro-6-methoxybenzofuran-2-carboxylate 

Downstream Products

• 90247-27-1 (R)-3-[(S)-8-Chloro-3-(2-fluoro-phenyl)-5,6-dihydro-furo[2',3':4,5]benzo[1,2-d]isoxazole-6-carbonyl]-4-phenyl-oxazolidin-2-one 
• 90247-26-0 (R)-3-[(R)-8-Chloro-3-(2-fluoro-phenyl)-5,6-dihydro-furo[2',3':4,5]benzo[1,2-d]isoxazole-6-carbonyl]-4-phenyl-oxazolidin-2-one 
• 90247-30-6 (S)-8-Chloro-3-(2-fluoro-phenyl)-5,6-dihydro-furo[2',3':4,5]benzo[1,2-d]isoxazole-6-carboxylic acid 
• 90247-29-3 (R)-8-Chloro-3-(2-fluoro-phenyl)-5,6-dihydro-furo[2',3':4,5]benzo[1,2-d]isoxazole-6-carboxylic acid 
• 90247-25-9 8-chloro-5,6-dihydro-3-(o-fluorophenyl)furo<3,2-f>-1,2-benzisoxazole-6-carbonyl chloride 

Relevant articles and documents

Substituted 5,6-dihydrofuro[3,2-f]-1,2-benzisoxazole-6-carboxylic acids: High-ceiling diuretics with uricosuric activity

A series of substituted 5,6-dihydrofuro[3,2-f]-1,2-benzisoxazoles was prepared and evaluated for their saluretic and uricosuric properties. Pharmacological evaluation of the title compounds was carried out in mice, rats, dogs, and monkeys. The diuretic/sa

Benzisoxazole carboxylic acids

Described are compounds of the formula STR1 wherein X is hydrogen, loweralkyl, halo, loweralkoxy or trifluoromethyl, and Z is hydrogen, loweralkyl, halo, hydroxy or alkoxy, or compounds of the formula STR2 wherein X' and Y' may be the same or different an