90508-20-6

Basic information

• Product Name: L-Phenylalanine, N-[(2-propenyloxy)carbonyl]-
• Synonyms: AmbotzAAA1705
• CAS NO: 90508-20-6
• Molecular Formula: C13H15NO4
• Molecular Weight: 249.266
• Mol File: 90508-20-6.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: L-Phenylalanine, N-[(2-propenyloxy)carbonyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: L-Phenylalanine, N-[(2-propenyloxy)carbonyl]-(90508-20-6)
• EPA Substance Registry System: L-Phenylalanine, N-[(2-propenyloxy)carbonyl]-(90508-20-6)

Safety Data

• Hazardous Substances Data: 90508-20-6(Hazardous Substances Data)

Usage

General Description

L-Phenylalanine, N-[(2-propenyloxy)carbonyl]- is a chemical compound with the molecular formula C13H13NO3. It is an ester derivative of the amino acid L-phenylalanine, containing a propenyl ester group attached to the nitrogen atom. L-Phenylalanine, N-[(2-propenyloxy)carbonyl]- is commonly used in the synthesis of peptide and protein-based drugs, as well as in the production of various pharmaceuticals and bioactive compounds. It has also been studied for its potential biological activities, including its role as an anti-inflammatory and anti-cancer agent. Additionally, L-Phenylalanine, N-[(2-propenyloxy)carbonyl]- may have applications in the food industry as a flavor enhancer and sweetener.

Upstream product

• 63-91-2 L-phenylalanine 
• 128369-71-1 (S)-methyl-(N-allyloxycarbonyl)phenylalaninate 
• 2577-90-4 methyl (2S)-2-amino-3-phenylpropanoate 
• 583-47-1 4-benzyl-oxazolidine-2,5-dione 
• 150-30-1 Phenylalanine 
• 35661-40-6 N-Fmoc L-Phe 
• 2937-50-0 Allyl chloroformate 
• 673-06-3 D-(R)-phenylalanine 
• 135544-68-2 N-(allyloxycarbonyloxy)succinimide 
• 394210-47-0 4-benzyl-2,5-dioxo-oxazolidine-3-carboxylic acid allyl ester 
• 115491-93-5 diallyl dicarbonate 

Downstream Products

• 90508-24-0 Aloc-Phe-Ser(tBu)-tert-butylester 
• 90508-27-3 Aloc-Phe-Ser-OH 
• 353491-45-9 Alloc-Phe-Thr-OtBu 

Relevant articles and documents

CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF BACKGROUND

Disclosed herein are small molecule calpain modulators, pharmaceutical compositions, preparation methods and their use as therapeutic agents. The therapeutic agents can be used for treating fibrotic disease or a resulting secondary disease state or condition. The small molecules can inhibit calpain through contact with CAPN1, CAPN2, and/or CAPN9 enzymes.

A mild copper catalyzed method for the selective deprotection of aryl allyl ethers

Copper boryl reagents enable the selective cleavage of aryl allyl ethers to the corresponding phenols in good to moderate yields.

Rational conversion of noncontinuous active region in proteins into a small orally bioavailable macrocyclic drug-like molecule: The HIV-1 CD4:gp120 paradigm

Rational conversion of noncontinuous active regions of proteins into a small orally bioavailable molecule is crucial for the discovery of new drugs based on inhibition of protein-protein interactions. We developed a method that utilizes backbone cyclization as an intermediate step for conversion of the CD4 noncontinuous active region into small macrocyclic molecules. We demonstrate that this method is feasible by preparing small inhibitor for human immunodeficiency virus infection. The lead compound, CG-1, proved orally available in the rat model.