945-49-3

Basic information

• Product Name: Cyclohexyl(phenyl)methanol
• Synonyms: cyclohexylphenyl-methano;Phenylcyclohexylmethanol;α-Cyclohexylbenzenemethanol;1-(5-Methyl-3-phenylisoxazol-4-yl)ethan-1-ol;4-(1-Hydroxyethyl)-5-methyl-3-phenylisoxazole;Cyclohexyl(phenyl)carbinol, [Hydroxy(phenyl)methyl]cyclohexane;CYCLOHEXYL(PHENYL)METHANOL;AURORA KA-6956
• CAS NO: 945-49-3
• Molecular Formula: C₁₃H₁₈O
• Molecular Weight: 190.28
• Product Categories: Phenyls & Phenyl-Het;Phenyls & Phenyl-Het
• Mol File: 945-49-3.mol
• Article Data: 242

Chemical Properties

• Melting Point: 48℃
• Boiling Point: 305.1°Cat760mmHg
• Flash Point: 128.1°C
• Appearance: /
• Density: 1.039g/cm³
• Vapor Pressure: 0.000368mmHg at 25°C
• Refractive Index: 1.55
• PKA: 14.36±0.20(Predicted)
• CAS DataBase Reference: Cyclohexyl(phenyl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexyl(phenyl)methanol(945-49-3)
• EPA Substance Registry System: Cyclohexyl(phenyl)methanol(945-49-3)

Safety Data

• Hazard Codes: Xi
• Safety Statements: S24/25:Avoid contact with skin and eyes.
• Hazardous Substances Data: 945-49-3(Hazardous Substances Data)

Usage

General Description

Cyclohexyl(phenyl)methanol, also known as cyclohexylbenzyl alcohol, is a chemical compound with the molecular formula C13H18O. It is a clear, colorless liquid with a faint aromatic odor. Cyclohexyl(phenyl)methanol is used in the production of various industrial and consumer products, such as fragrances, flavorings, and pharmaceuticals. It can also be used as a solvent, a catalyst in chemical reactions, and a chemical intermediate in the manufacturing of other organic compounds. Cyclohexyl(phenyl)methanol has mild to moderate acute toxicity and should be handled and used with appropriate safety precautions to prevent exposure and potential health risks.

InChI:InChI=1/C13H18O/c14-13(11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1,3-4,7-8,12-14H,2,5-6,9-10H2

Upstream product

• 69578-07-0 2-chloro-cycloheptanol 
• 60-29-7 diethyl ether 
• 931-51-1 cyclohexylmagnesiumchloride 
• 100-52-7 benzaldehyde 
• 712-50-5 Cyclohexyl phenyl ketone 
• 16635-23-7 phenyltriisopropoxytitanium(IV) 
• 2043-61-0 cyclohexanecarbaldehyde 
• 51367-94-3 Diphenyltitandichlorid 
• 98-80-6 phenylboronic acid 
• 16224-09-2 benzyl cyclohexyl ether 
• 693-03-8 n-butyl magnesium bromide 
• 960-71-4 triphenylborane 
• 78-79-5 isoprene 
• 1078-58-6 diphenylzinc 

Downstream Products

• 4714-09-4 1-benzylcyclohexene 
• 72955-04-5 N-(cyclohexyl-phenyl-methyl)-benzamide 
• 126979-61-1 cyclohexyl(methoxy)phenylmethane 
• 1608-31-7 (cyclohexylidenemethyl)benzene 
• 4410-75-7 (cyclohexylmethyl)benzene 
• 712-50-5 Cyclohexyl phenyl ketone 
• 13694-42-3 (+/-)-cylohexylphenylmethyl hydroperoxide 
• 916249-66-6 (1-cyclohexyl-4-methylpent-3-enyl)benzene 
• 916249-80-4 methyl 3-cyclohexyl-3-hydroxy-3-phenylpropanoate 
• 46498-49-1 3-Cyclohexyl-3-phenylpropanal 
• 108667-55-6 1-cyclohexyl-1-phenylpropane-1,3-diol 
• 121314-51-0 3-Cyclohexyl-3-phenyl-1-propanol 
• 101872-44-0 1-(cyclohexyl-phenyl-methyl)-4-methyl-piperazine 
• 102019-53-4 1-ethyl-4-(cyclohexyl-phenyl-methyl)-piperazine 

Relevant articles and documents

Bio-inspired asymmetric aldehyde arylations catalyzed by rhodium-cyclodextrin self-inclusion complexes

Transition-metal catalysts are powerful tools for carbon-carbon bond-forming reactions that are difficult to achieve using native enzymes. Enzymes that exhibit inherent selectivities and reactivities through host-guest interactions have inspired widesprea

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The asymmetric transfer hydrogenation (ATH) of a wide range of ketones catalyzed by manganese complex as well as chiral PxNy-type ligand under mild conditions was investigated. Using 2-propanol as hydrogen source, various ketones could be enantioselectively hydrogenated by combining cheap, readily available [MnBr(CO)5] with chiral, 22-membered macrocyclic ligand (R,R,R',R')-CyP2N4 (L5) with 2 mol% of catalyst loading, affording highly valuable chiral alcohols with up to 95% ee.

Ir(NHC)-Catalyzed Synthesis of β-Alkylated Alcohols via Borrowing Hydrogen Strategy: Influence of Bimetallic Structure

Multi N-heterocyclic carbene(NHC)-modified iridium catalysts were employed in the β-alkylation of alcohols; dimerization of primary alcohols (Guerbet reaction), cross-coupling of secondary and primary alcohols, and intramolecular cyclization of alcohols. Mechanistic studies of Guerbet reaction, including kinetic experiments, mass analysis, and density functional theory (DFT) calculation, were employed to explain the fast reaction promoted by bimetallic catalysts, and the dramatic reactivity increase of monometallic catalysts at the late stage of the reaction. (Figure presented.).