949449-09-6

Basic information

• Product Name: (E)-ethyl 3-(5-fluoro-2-hydroxyphenyl)acrylate
• Synonyms: (E)-ethyl 3-(5-fluoro-2-hydroxyphenyl)acrylate
• CAS NO: 949449-09-6
• Molecular Formula: C₁₁H₁₁FO₃
• Molecular Weight: 210.2016432
• Mol File: 949449-09-6.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (E)-ethyl 3-(5-fluoro-2-hydroxyphenyl)acrylate(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-ethyl 3-(5-fluoro-2-hydroxyphenyl)acrylate(949449-09-6)
• EPA Substance Registry System: (E)-ethyl 3-(5-fluoro-2-hydroxyphenyl)acrylate(949449-09-6)

Safety Data

• Hazardous Substances Data: 949449-09-6(Hazardous Substances Data)

Usage

General Description

(E)-ethyl 3-(5-fluoro-2-hydroxyphenyl)acrylate, also known as Ethyl ferulate, is a chemical compound with the molecular formula C12H12O4F. It is a ester of ferulic acid, a natural phenolic compound found in various plants. This chemical is commonly used in the synthesis of organic compounds and pharmaceutical products. It is known for its potential anti-inflammatory, antioxidant, and antimicrobial properties. (E)-ethyl 3-(5-fluoro-2-hydroxyphenyl)acrylate has also been studied for its potential use in cosmetics and skincare products. Overall, this compound has a wide range of potential applications due to its unique chemical properties.

Upstream product

• 496-69-5 2-bromo-4-fluoro-phenol 
• 140-88-5 ethyl acrylate 
• 347-54-6 5-fluoro-2-hydroxybenzaldehyde 
• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 1099-45-2 ethyl (triphenylphosphoranylidene)acetate 

Downstream Products

• 949448-98-0 C₁₅H₁₃O₄F 
• 1134885-95-2 6-fluoro-3,4-dihydro-4-phenylcoumarin 
• 75487-82-0 6-fluoro-2H-chromen-2-one 

Relevant articles and documents

Free radical scavenging and α-glucosidase inhibitory activity of (E)-methyl/ethyl-3-(2-hydroxyphenyl)acrylates

(E)-Methyl/ethyl-3-(2-hydroxyphenyl)acrylates 3a-x have been prepared by the reaction of salicylaldehydes 1a-l with Wittig reagents such as methyl (triphenylphosphoranylidene)acetate 2a and ethyl (triphenylphosphoranylidene)acetate 2b in dry DCM at room t

Rh-Catalyzed Deformylative Coupling of Salicylaldehydes with Acrylates and Acrylamides

An unprecedented deformylative coupling of salicylaldehydes to acrylates and acrylamides under Rh-catalyzed conditions is reported. These deformylative couplings afforded o-hydroxycinnamates and o-hydroxycinnamamides with broad functional group tolerance and high chemoselectivity under milder reaction conditions.

Rhodium-catalyzed domino conjugate addition-cyclization reactions for the synthesis of a variety of N- and O-heterocycles: Arylboroxines as effective carbon nucleophiles

Facile and efficient Rh(I)-catalyzed domino conjugate addition-cyclization reactions of olefins bearing two electrophilic sites and a pendant nucleophile with organoboroxines have been developed to afford a variety of N- and O-heterocycles, such as 3,4-dihydroquinolin-2(1H)-ones, 3,4-dihydrocoumarins, and pyrrolidin-2-ones, which constitute important motifs in biologically active natural and synthetic organic compounds.