96316-04-0

Basic information

• Product Name: Benzenecarbothioamide, N-(2-hydroxyethyl)-4-methoxy-
• CAS NO: 96316-04-0
• Molecular Formula: C10H13NO2S
• Molecular Weight: 211.285
• Mol File: 96316-04-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzenecarbothioamide, N-(2-hydroxyethyl)-4-methoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenecarbothioamide, N-(2-hydroxyethyl)-4-methoxy-(96316-04-0)
• EPA Substance Registry System: Benzenecarbothioamide, N-(2-hydroxyethyl)-4-methoxy-(96316-04-0)

Safety Data

• Hazardous Substances Data: 96316-04-0(Hazardous Substances Data)

Upstream product

• 100-07-2 4-methoxy-benzoyl chloride 
• 57728-69-5 N-(2-hydroxyethyl)-p-methoxybenzamide 
• 2362-64-3 p-methoxythiobenzamide 
• 141-43-5 ethanolamine 
• 123-11-5 4-methoxy-benzaldehyde 

Downstream Products

• 2519-93-9 2-(4-methoxyphenyl)-4,5-dihydro-1,3-thiazole 
• 13676-94-3 2-(4-methoxyphenyl)-4,5-dihydrooxazole 
• 96160-03-1 2-(4-Methoxy-phenyl)-3-methyl-4,5-dihydro-thiazol-3-ium; iodide 

Relevant articles and documents

Microwave-Assisted Synthesis of 2-Substituted 2-Thiazolines and 5,6-Dihydro-4 H -1,3-thiazines

An efficient and general method for the synthesis of 2-substituted thiazolines and 5,6-dihydro-4 H -1,3-thiazines is developed via microwave-assisted ring closure of ω-thioamidoalcohols promoted by ethyl polyphosphate (PPE). The cyclization reaction involves an S N 2-type mechanism and features the advantages of very short reaction times, high yields and a predictable stereochemical outcome. The acyclic precursors are prepared in high overall yields by an improved diacylation-thionation-saponification sequence from commercially available ω-amino alcohols. The whole process is metal-free and operationally simple.

Research on radioprotective agents: Δ-2 Thiazolines and homologous derivatives

Compounds derived from Δ-2 thiazoline, Δ-2 thiazolinium iodoalkylate and 4,5-dihydro-1,3 thiazine have been prepared and evaluated as potential antiradiation agents in mice. They generally have a low toxicity and significant radioprotective activity.