Synthesis of quercinol

March 11, 2024

• Title:       

  Synthesis of quercinol

• Image Source:

  Synthesis and J-Dimer Formation of Tetrapyrazinoporphyrazines with Different Functional Groups for Potential Biomolecular Probe Applications

• Mark:

  Scheme 1

• Associated context:

  Although several synthetic approaches for accessing low-symmetry TPyzPzs have been published, the statistical condensation of two different precursors, i.e., 5,6-disubstituted pyrazine-2,3-dicarbonitriles, remains the most commonly used method. Suitable precursors were prepared from 5,6-dichloropyrazine-2,3-dicarbonitrile (11) by nucleophilic substitution using the appropriate nucleophiles (Scheme 1).