2-Furanethanol

Base Information

• Chemical Name: 2-Furanethanol
• CAS No.: 35942-95-1
• Molecular Formula: C6H8O2
• Molecular Weight: 112.128
• Hs Code.: 2932190090
• European Community (EC) Number: 854-935-1
• DSSTox Substance ID: DTXSID40348978
• Nikkaji Number: J1.356.910J
• Wikidata: Q82123981
• Mol file: 35942-95-1.mol

Synonyms:2-furanethanol;35942-95-1;2-(furan-2-yl)ethanol;beta-2-Furylethanol;2-furan-2-yl-ethanol;2-(furan-2-yl)ethan-1-ol;B-2-FURYLETHANOL;2-(2-furyl)ethanol;Furan-2-ethanol;a-Furfurylcarbinol;2-(2-Hydroxyethyl)furan;SCHEMBL1532367;DTXSID40348978;MFCD00798037;AKOS013265773;SB36813;AS-56798;CS-0047160;EN300-103377;W10532;Z1179944660

Chemical Property of 2-Furanethanol

Chemical Property:

• Boiling Point: 96-97 °C(Press: 42 Torr)
• PKA: 14.83±0.10(Predicted)
• PSA: 33.37000
• Density: 1.4788 g/cm3(Temp: 25 °C)
• LogP: 0.81440
• XLogP3: 1.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 112.052429494
• Heavy Atom Count: 8
• Complexity: 63.5

Purity/Quality:

NLT 98% ^*data from raw suppliers

2-(furan-2-yl)ethanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=COC(=C1)CCO

Technology Process of 2-Furanethanol

There total 3 articles about 2-Furanethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

2-(2-furyl)ethyl β-glucopyranoside (1021922-51-9) + ethyl acetoacetate (141-97-9) → 2-(furan-2-yl)ethanol (35942-95-1) + ethyl 2-methyl-5-(D-arabino-tetritol-1-yl)furan-3-carboxylate (3351-43-7)

Guidance literature:

In 1,4-dioxane; water; for 6h; Heating;

DOI:10.1002/ejoc.200700717

Reference yield:

2-furyloxirane (2745-17-7) → 1-(2-furyl)ethanol (4208-64-4) + 2-(furan-2-yl)ethanol (35942-95-1)

Guidance literature:

With sodium tetrahydroborate; In tert-butyl alcohol; for 2h; Yield given. Yields of byproduct given; Ambient temperature;

Reference yield:

(furan-2-yl)ethylene (1487-18-9) → 2-(furan-2-yl)ethanol (35942-95-1) + (S)-1-(2-furanyl)ethanol (4208-64-4,27948-61-4,106565-48-4,112653-32-4) + (R)-(+)-1-(2-furyl)ethanol (27948-61-4)

Guidance literature:

(furan-2-yl)ethylene; With benzo[1,3,2]dioxaborole; rhodium complex 2; In toluene; at 20 ℃; for 2h;

With sodium hydroxide; water; dihydrogen peroxide; In toluene; at 20 ℃; for 2h; Title compound not separated from byproducts;

DOI:10.1002/(SICI)1521-3765(19990401)5:4<1320::AID-CHEM1320>3.0.CO;2-#

upstream raw materials:

2-furyloxirane

(furan-2-yl)ethylene

2-(2-furyl)ethyl β-glucopyranoside

ethyl acetoacetate

Downstream raw materials:

(2-(tetrahydro-furan-2-yl)-ethanol)

2-<2-(benzyloxy)ethyl>furan

2-[2-(4-Nitro-phenoxy)-ethyl]-furan

2-Bromo-1-(2'-furyl)ethane

Refernces

• 1、 Doucet, Henri,Fernandez, Elena,Layzell, Timothy P.,Brown, John M.. "The scope of catalytic asymmetric hydroboration/oxidation with rhodium complexes of 1,1'-(2-diarylphosphino-1-naphthyl)isoquinolines". . p. 1320 - 1330. Retrieved 2007/10/03.