2-Propanone, methylphenylhydrazone

Base Information

• Chemical Name: 2-Propanone, methylphenylhydrazone
• CAS No.: 3741-86-4
• Molecular Formula: C10H14N2
• Molecular Weight: 162.235
• Mol file: 3741-86-4.mol

Synonyms:

Chemical Property of 2-Propanone, methylphenylhydrazone

Chemical Property:

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Propanone, methylphenylhydrazone

There total 6 articles about 2-Propanone, methylphenylhydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

1-Methyl-1-phenylhydrazine (618-40-6) + 1-(2-phenylethynyl)-1-cyclobutanol (308805-77-8) → acetone methylphenylhydrazone (3741-86-4) + 1‐methyl‐3‐phenyl‐1H‐indazole (51093-42-6)

Guidance literature:

With silver hexafluoroantimonate; dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; zinc diacetate; In toluene; at 50 ℃; for 24h; Inert atmosphere;

DOI:10.1039/c9cc08884a

Reference yield:

1-Methyl-1-phenylhydrazine (618-40-6) + toluene (108-88-3,15644-74-3,16713-13-6) + acetone semicarbazone (110-20-3) → hydrazodicarboxamide (110-21-4) + 5-isopropylidene-1-methyl-1-phenyl carbonohydrazide + acetone methylphenylhydrazone (3741-86-4)

Guidance literature:

at 130 - 135 ℃;

Reference yield:

N-methyl-N-nitrosoaniline (614-00-6) → acetone methylphenylhydrazone (3741-86-4)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium hydroxide; Aminoiminomethanesulfinic acid / methanol / 50 °C

2: dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; silver hexafluoroantimonate; zinc diacetate / toluene / 24 h / 50 °C / Inert atmosphere

With silver hexafluoroantimonate; dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; zinc diacetate; Aminoiminomethanesulfinic acid; sodium hydroxide; In methanol; toluene;

DOI:10.1039/c9cc08884a

upstream raw materials:

1-Methyl-1-phenylhydrazine

acetone

toluene

acetone semicarbazone

Downstream raw materials:

N-methyl-N-nitrosoaniline

N-acetyl-N-methylaniline

N'-methyl-N'-phenylacetohydrazide

trans-bis(acetone methylphenylhydrazone)dichloropalladium(II)

Refernces