1-Bromodibenzofuran

Base Information

• Chemical Name: 1-Bromodibenzofuran
• CAS No.: 50548-45-3
• Molecular Formula: C12H7BrO
• Molecular Weight: 247.091
• Hs Code.: 2932999099
• European Community (EC) Number: 837-464-6
• DSSTox Substance ID: DTXSID20145866
• Nikkaji Number: J2.273.419I
• Wikidata: Q72454040
• Mol file: 50548-45-3.mol

Synonyms:1-bromodibenzo[b,d]furan;1-Bromodibenzofuran;50548-45-3;1-bromo-dibenzofuran;bromodibenzofuran;103456-35-5;Dibenzofuran, bromo-;MFCD00094238;1-Bromdibenzofuran;SCHEMBL1536858;AMY8831;DTXSID20145866;CS-D0502;AKOS016012343;DS-6886;OL10177;SY111975;B5766;FT-0701190;F50552;A850833;A855606

Chemical Property of 1-Bromodibenzofuran

Chemical Property:

• Vapor Pressure: 0.000136mmHg at 25°C
• Melting Point: 67℃
• Boiling Point: 343.8±15.0 °C(Predicted)
• PSA: 13.14000
• Density: 1.577±0.06 g/cm3(Predicted)
• LogP: 4.34850
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 4.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 245.96803
• Heavy Atom Count: 14
• Complexity: 218

Purity/Quality:

99%Min ^*data from raw suppliers

1-Bromodibenzofuran ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C3=C(O2)C=CC=C3Br
• Uses: 1-bromodibenzo[b,d]furan can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development and chemical and pharmaceutical production processes.

Technology Process of 1-Bromodibenzofuran

There total 19 articles about 1-Bromodibenzofuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

→ 1-bromodibenzo[b,d]furan (50548-45-3)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; at 0 - 100 ℃; for 1.33333h;

Reference yield: 88.5%

6’-bromo-2’-fluoro-biphenyl-2-ol → 1-bromodibenzo[b,d]furan (50548-45-3)

Guidance literature:

With sodium hydride; In water; N,N-dimethyl-formamide; paraffin oil; at 5 - 100 ℃; for 1.08333h;

Reference yield: 80.0%

2,3-diethynylbenzo[b]furan → 1-bromodibenzo[b,d]furan (50548-45-3)

Guidance literature:

With hydrogen bromide; platinum(II) chloride; In water; at 100 ℃; for 3h;

DOI:10.1021/jo0518295

upstream raw materials:

1-bromo-dibenzofuran-2-ylamine

1-bromodibenzo[b,d]furan-1-amine

dibenzo[b,d]furan-2-amine

4-aminodibenzofuran

Downstream raw materials:

1-aminodibenzofuran

Dibenzofuran-1-carboxylic acid

4-nitro-5-trans-styryl-thiophene-2-carboxylic acid methyl ester

dibenzo[b,d]furan-1-yl-boronic acid

Refernces

• 1、 -. "COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE". Paragraph 0341; 0345. . Retrieved 2020/12/25.
• 2、 -. "MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES". . . Retrieved 2019/05/07.