1,3-Propanediol diacrylate

Base Information

• Chemical Name: 1,3-Propanediol diacrylate
• CAS No.: 24493-53-6
• Molecular Formula: C9H12O4
• Molecular Weight: 184.192
• Hs Code.: 2916190090
• European Community (EC) Number: 246-287-8
• DSSTox Substance ID: DTXSID40879550
• Nikkaji Number: J175.481E
• Wikidata: Q82861662
• Mol file: 24493-53-6.mol

Synonyms:1,3-Propanediol diacrylate;24493-53-6;Propane-1,3-diyl diacrylate;1,3-propanedioldiacrylate;1,3-Propanediyl diacrylate;3-prop-2-enoyloxypropyl prop-2-enoate;EINECS 246-287-8;2-Propenoic acid, 1,3-propanediyl ester;2-Propenoic acid, 1,1'-(1,3-propanediyl) ester;PDDA;SCHEMBL321925;DTXSID40879550;MFCD00078387;AKOS006345702;BS-53229;FT-0690887;E85337

Chemical Property of 1,3-Propanediol diacrylate

Chemical Property:

• Vapor Pressure: 0.0327mmHg at 25°C
• Refractive Index: 1.449
• Boiling Point: 243.1 °C at 760 mmHg
• Flash Point: 113.8 °C
• PSA: 52.60000
• Density: 1.057 g/cm³
• LogP: 0.83490
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 8
• Exact Mass: 184.07355886
• Heavy Atom Count: 13
• Complexity: 186

Purity/Quality:

98%Min ^*data from raw suppliers

1,3-PROPANEDIOL DIACRYLATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C=CC(=O)OCCCOC(=O)C=C

Technology Process of 1,3-Propanediol diacrylate

There total 4 articles about 1,3-Propanediol diacrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

acryloyl chloride (814-68-6,25189-84-8) + trimethyleneglycol (504-63-2) → 2-propenoic acid 1,3-propanediyl ester (24493-53-6)

Guidance literature:

In N,N-dimethyl acetamide; at 0 - 20 ℃; for 24h;

Reference yield:

acrylic acid methyl ester (292638-85-8,9003-21-8,96-33-3) + trimethyleneglycol (504-63-2) → 2-propenoic acid 1,3-propanediyl ester (24493-53-6) + 3-hydroxypropyl acrylate (2761-08-2)

Guidance literature:

With Novozyme 435; In 2-methyl-2-butanol; at 50 ℃; for 24h; Enzymatic reaction;

DOI:10.1002/pola.24041

Reference yield:

3-Bromo-propionic acid 3-(3-bromo-propionyloxy)-propyl ester (53219-89-9) → 2-propenoic acid 1,3-propanediyl ester (24493-53-6)

Guidance literature:

With triethylamine; hydroquinone; In benzene; Heating;

DOI:10.1002/jps.2600630734

upstream raw materials:

3-Bromo-propionic acid 3-(3-bromo-propionyloxy)-propyl ester

acryloyl chloride

trimethyleneglycol

acrylic acid methyl ester

Downstream raw materials:

3-[1-(3,4-Dimethoxy-benzyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-propionic acid 3-{3-[1-(3,4-dimethoxy-benzyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-propionyloxy}-propyl ester; compound with oxalic acid

Refernces

• 1、 Popescu, Dragos,Hoogenboom, Richard,Keul, Helmut,Moeller, Martin. "Free radical and nitroxide mediated polymerization of hydroxy-functional acrylates prepared via lipase-catalyzed transacylation reactions". experimental part. p. 2610 - 2621. Retrieved 2011/04/22.
• 2、 Stenlake,Waigh,Dewar,et al.. "Biodegradable neuromuscular blocking agents. Part 4. Atracurium besylate and related polyalkylene di-esters". . p. 515 - 524. Retrieved 2007/10/02.