Ethanamine, 2,2'-oxybis-

Base Information

• Chemical Name: Ethanamine, 2,2'-oxybis-
• CAS No.: 2752-17-2
• Molecular Formula: C4H12N2O
• Molecular Weight: 104.152
• Hs Code.: 29221990
• European Community (EC) Number: 220-395-5
• UNII: FFW1773ZZ6
• DSSTox Substance ID: DTXSID7041914
• Nikkaji Number: J136.430H
• Wikidata: Q27277963
• ChEMBL ID: CHEMBL3183428
• Mol file: 2752-17-2.mol

Synonyms:2752-17-2;2,2'-oxydiethanamine;1,5-Diamino-3-oxapentane;2-(2-aminoethoxy)ethanamine;Ethanamine, 2,2'-oxybis-;2,2'-Oxybis(ethylamine);Amino-PEG1-Amine;Bis(2-aminoethyl) Ether;2,2-oxybis(ethylamine);aminoethyl ether;2,2'-Oxybis(ethanamine);EINECS 220-395-5;2,2'-Oxydi(ethylamine);UNII-FFW1773ZZ6;FFW1773ZZ6;2,2'-oxybis(ethan-1-amine);DTXSID7041914;2-(2-aminoethoxy)ethan-1-amine;MFCD00466591;EC 220-395-5;2,2'-Oxydiethylamine;2,2'-Diaminodiethyl Ether;2-(2-Aminoethoxy)ethylamine;diamino-PEG;di-amino-PEG;2-aminoethyl ether;bis(2-aminoethyl)ether;2,2'-Oxybisethanamine;22-Oxybis(ethylamine);3-oxa-1,5-diaminopentane;3-oxa-1,5-pentanediamine;JEFFAMINE EDR 104;SCHEMBL55912;2-(2-Aminoethoxy)ethylamine #;CHEMBL3183428;DTXCID5021914;CHEBI:53541;GXVUZYLYWKWJIM-UHFFFAOYSA-;2,2'-OXYDI(ETHANAMINE);Amine-PEG-amine, MW 1,000;Amine-PEG-amine, MW 2,000;Amine-PEG-amine, MW 3,400;Amine-PEG-amine, MW 5,000;1,5-DIAMINE-3-OXAPENTANE;Amine-PEG-amine, MW 10,000;Amine-PEG-amine, MW 20,000;Amine-PEG-amine, MW 35,000;ETHYLAMINE, 2,2'-OXYBIS-;{2-[(2-aminoethyl)oxy]ethyl}amine;Tox21_301395;2,2'-OXY-BIS-(ETHYLAMINE);AKOS002312457;DS-7453;SB75599;Amine-PEG-amine HCl salt, MW 2,000;NCGC00255817-01;2-(2-Aminoethoxy)ethylamine, AldrichCPR;BP-13435;BP-23107;BP-23403;BP-23404;BP-23681;BP-23682;BP-23683;BP-25179;BP-25180;BP-29738;SY052726;CAS-2752-17-2;HY-140208;CS-0114847;FT-0650971;O0278;EN300-316362;2,2 inverted exclamation mark -Oxybis(ethylamine);Q27277963

Chemical Property of Ethanamine, 2,2'-oxybis-

Chemical Property:

• Appearance/Colour: clear colorless liquid
• Vapor Pressure: 2.39hPa at 20℃
• Refractive Index: 1.455-1.458
• Boiling Point: 185.893 °C at 760 mmHg
• PKA: pK1: 8.62(+2);pK2: 9.59(+1) (30°C)
• Flash Point: 74.784 °C
• PSA: 61.27000
• Density: 0.961 g/cm³
• LogP: 0.32100
• Storage Temp.: 2-8°C(protect from light)
• Water Solubility.: 100g/L at 20℃
• XLogP3: -1.8
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 104.094963011
• Heavy Atom Count: 7
• Complexity: 28.9

Purity/Quality:

99.9% ^*data from raw suppliers

2,2''-Oxydiethanamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C
• Statements: 34-41
• Safety Statements: 45-36/37/39-26-39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C(COCCN)N
• Description: Amino-PEG1-Amine is a water soluble PEG linker containing two amino groups. The amino groups are reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
• Uses: 2,2''-Oxydiethanamine is a coating resin modifier.

Technology Process of Ethanamine, 2,2'-oxybis-

There total 17 articles about Ethanamine, 2,2'-oxybis- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

2-(2-aminoethoxy)ethanamine dihydrochloride (60792-79-2) → 2,2'-diaminodiethyl ether (2752-17-2)

Guidance literature:

With ammonia; In methanol; chloroform;

DOI:10.1021/ja00271a031

Reference yield: 93.0%

2,2'-diphthalimido-diethyl ether (43113-25-3) → 2,2'-diaminodiethyl ether (2752-17-2)

Guidance literature:

With hydrazine hydrate; In chloroform; for 4h; Reflux;

DOI:10.1016/j.tet.2016.05.068

Reference yield: 90.0%

1,5-diazido-3-oxapentane (24345-74-2) → 2,2'-diaminodiethyl ether (2752-17-2)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; for 18h;

DOI:10.1039/c7cc03252h

upstream raw materials:

ethanolamine

1,5-diazido-3-oxapentane

2,2'-diphthalimido-diethyl ether

2-(2-aminoethoxy)ethanamine dihydrochloride

Downstream raw materials:

tetraacetate

Kryptofix 21

1,4,7,13-tetraoxa-10,16-diazacyclooctadecane

C₃₄H₅₄N₄O₉S₂

Refernces

• 1、 Shi, Xinkui,Mao, Shanshan,Shen, Kesheng,Wu, Huilu,Tang, Xia. "Synthesis, crystal structure, antioxidation and fluorescence of two lanthanide complexes with a noncyclic polyether Schiff base ligand". . p. 2015 - 2028. Retrieved 2017.
• 2、 Kato, Asako,Nagatsuka, Yusuke,Hiratsuka, Tomokazu,Kiuchi, Satoko,Iwase, Yoko,Okuno, Yuri,Tsukamoto, Tetsuya,Kiran,Sakai, Norio,Konakahara, Takeo. "Synthesis and cytotoxic activity of novel 11-methyl-6H-pyrido[4,3-b]carbazole derivatives linked to amine, N-methylurea, and N-methyl-N-nitrosourea moieties with various types of carbamoyl tethers at the C-5 atom". . p. 4258 - 4272. Retrieved 2016.
• 3、 Nelson S. Martin,Knox C. Victor. "Dicopper(II) Complexes of an N6O2 Macrocycle and Seven-co-ordinate Manganese(II), Iron(II), Cobalt(II), Nickel(II), Copper(II), and Zinc(II) Complexes of its N5O2 Open-chain Precursor". . p. 2525 - 2528. Retrieved 1983.
• 4、 Apfel, Ulf-Peter,Battistella, Beatrice,Gerschel, Philipp,Ray, Kallol,Siegmund, Daniel. "Electrochemical CO2 Reduction-The Effect of Chalcogenide Exchange in Ni-Isocyclam Complexes". . p. 1497 - 1510. Retrieved 2020/04/30.
• 5、 -. "Synthesis method of 2'-oxydiethylamine and product thereof". Page/Page column 6-9. . Retrieved 2019/08/12.