Technology Process of Acipimox
There total 10 articles about Acipimox which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
2-methylpyrazin-5-carboxylic acid;
With
hydrogenchloride;
In
water;
for 0.5h;
With
peracetic acid;
In
water;
at 20 ℃;
for 3h;
Reagent/catalyst;
Temperature;
- Guidance literature:
-
5-methyl-pyrazine-2,3-dicarboxylic acid;
With
sulfuric acid;
at 60 ℃;
for 1h;
With
sodium tungstate (VI) dihydrate; dihydrogen peroxide;
In
water;
for 8h;
Reagent/catalyst;
Temperature;
- Guidance literature:
-
2-methylquinoxaline;
With
potassium permanganate;
In
water;
at 80 - 105.5 ℃;
for 0.75h;
With
sulfuric acid;
In
water;
at 80 - 110 ℃;
for 1h;
With
potassium tungstate; dihydrogen peroxide;
In
water;
at 45 - 70 ℃;
for 3h;