Disulfide, bis(2-methoxyphenyl)

Base Information

• Chemical Name: Disulfide, bis(2-methoxyphenyl)
• CAS No.: 13920-94-0
• Molecular Formula: C14H14 O2 S2
• Molecular Weight: 278.396
• Hs Code.: 2930909090
• DSSTox Substance ID: DTXSID00930393
• Nikkaji Number: J109.733D
• Wikidata: Q82905736
• Mol file: 13920-94-0.mol

Synonyms:Disulfide, bis(2-methoxyphenyl);13920-94-0;2-methoxyphenyldisulphide;1-Methoxy-2-[(2-methoxyphenyl)disulfanyl]benzene;Disulfide, bis(o-methoxyphenyl);bis(2-methoxyphenyl)disulfide;SCHEMBL943297;bis(2-methoxyphenyl) disulfide;bis-(2-methoxyphenyl)disulfide;Bis(2-methoxyphenyl) persulfide;DTXSID00930393;AKOS030228285;1,1'-Disulfanediylbis(2-methoxybenzene);1-Methoxy-2-[(2-methoxyphenyl)disulfanyl]benzene #

Chemical Property of Disulfide, bis(2-methoxyphenyl)

Chemical Property:

• Vapor Pressure: 1.41E-05mmHg at 25°C
• Boiling Point: 378°Cat760mmHg
• Flash Point: 182.4°C
• PSA: 69.06000
• Density: 1.24g/cm³
• LogP: 4.50320
• XLogP3: 4.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 278.04352203
• Heavy Atom Count: 18
• Complexity: 214

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=CC=C1SSC2=CC=CC=C2OC

Technology Process of Disulfide, bis(2-methoxyphenyl)

There total 27 articles about Disulfide, bis(2-methoxyphenyl) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2-Methoxybenzenethiol (7217-59-6) → bis(2-methoxyphenyl)disulfide (13920-94-0)

Guidance literature:

With N,N,N,N,-tetramethylethylenediamine; eosin y; In ethanol; for 4h; Irradiation;

DOI:10.1002/adsc.201401010

Reference yield: 97.0%

(C6H5)4SbSC6H4OCH3*0.5CHCl3 → biphenyl (92-52-4,1594-86-1) + bis(2-methoxyphenyl)disulfide (13920-94-0) + 1-methoxy-2-(phenylthio)benzene (14065-22-6) + triphenylantimony (603-36-1) + benzene (71-43-2,26181-88-4,54682-86-9,13967-78-7,174973-66-1)

Guidance literature:

In neat (no solvent); thermal decompn. of Sb compd. in a sealed tube on heating to 140°C for 3 h; not isolated, detected by GLC and TLC;

DOI:10.1016/S0022-328X(00)83047-8

Reference yield: 89.0%

4-iodoanisol (529-28-2) → bis(2-methoxyphenyl)disulfide (13920-94-0)

Guidance literature:

With morpholinium morpholine-1-carbodithioate; copper(l) chloride; potassium hydroxide; In water; N,N-dimethyl-formamide; at 110 ℃; for 20h; Green chemistry;

DOI:10.1080/17415993.2015.1031135

upstream raw materials:

2-Methoxybenzenethiol

S-(2-methoxyphenyl) ethanethioate

2-Methoxyphenylmercuric chloride

2,5-dichloroacetophenone

Downstream raw materials:

o-methoxybenzenesulfenyl chloride

1-methoxy-2-[(trifluoromethyl)sulfanyl]benzene

1-methoxy-2-(phenylthio)benzene

C₁₆H₁₃NO₃S

Refernces

• 1、 Dutta, Pratip Kumar,Majumder, Arpi,Dutta, Sanjay,Dhar, Basab Bijayi,Munshi, Parthapratim,Sen, Subhabrata. "Solvent free, palladium catalyzed highly facile synthesis of diaryl disulfides from aryl thiols". . p. 527 - 530. Retrieved 2017.
• 2、 Cacciola,Fevig,Alexander,Brittelli,Kettner,Knabb,Weber. "Synthesis of conformationally-restricted boropeptide thrombin inhibitors". . p. 301 - 306. Retrieved 1996.
• 3、 -. "Preparation method of symmetric disulfide bond-containing compound". Paragraph 0020; 0051-0053. . Retrieved 2021/11/21.
• 4、 Zhou, Jing-Ya,Zhu, Yong-Ming. "Forging C?S(Se) Bonds by Nickel-catalyzed Decarbonylation of Carboxylic Acid and Cleavage of Aryl Dichalcogenides". . p. 2452 - 2461. Retrieved 2021/06/28.