1,3-Dichloro-1,1,2,2,3,3-hexafluoropropane

Base Information

• Chemical Name: 1,3-Dichloro-1,1,2,2,3,3-hexafluoropropane
• CAS No.: 662-01-1
• Molecular Formula: C3Cl2 F6
• Molecular Weight: 220.929
• European Community (EC) Number: 211-552-9
• DSSTox Substance ID: DTXSID90216375
• Nikkaji Number: J205.961D
• Wikidata: Q83092596
• Mol file: 662-01-1.mol

Synonyms:662-01-1;1,3-DICHLOROHEXAFLUOROPROPANE;1,3-Dichloro-1,1,2,2,3,3-hexafluoropropane;EINECS 211-552-9;CFC-216ca;SCHEMBL1990770;Hexafluorotrimethylene dichloride;DTXSID90216375;Propane, 1,3-dichlorohexafluoro-;MFCD00018815;AKOS015848747;LS-119963;FT-0606651;1,3-dichloro-1,1,2,2,3,3-hexafluoro-propane;Propane, 1,3-dichloro-1,1,2,2,3,3-hexafluoro-

Chemical Property of 1,3-Dichloro-1,1,2,2,3,3-hexafluoropropane

Chemical Property:

• Vapor Pressure: 494mmHg at 25°C
• Refractive Index: 1.303
• Boiling Point: 35-36°C
• PSA: 0.00000
• Density: 1,573 g/cm³
• LogP: 3.28490
• XLogP3: 3.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 2
• Exact Mass: 219.9281244
• Heavy Atom Count: 11
• Complexity: 138

Purity/Quality:

98%min ^*data from raw suppliers

1,3-Dichlorohexafluoropropane 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Low toxicity by inhalation.
• Hazard Codes: Xi
• Statements: 59
• Safety Statements: 23-36/37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C(C(F)(F)Cl)(C(F)(F)Cl)(F)F

Technology Process of 1,3-Dichloro-1,1,2,2,3,3-hexafluoropropane

There total 21 articles about 1,3-Dichloro-1,1,2,2,3,3-hexafluoropropane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

polytetrafluoroethylene (116-14-3,82785-14-6) + trichlorofluoromethane (75-69-4) → 1,3-dichlorohexafluoropropane (662-01-1) + freon-214 (2268-46-4) + 1,1-dichlorohexafluoropropane (2729-28-4) + 1,1,1-trichloro-2,2,3,3,3-pentafluoropropane (4259-43-2)

Guidance literature:

With aluminium trichloride; at 30 - 50 ℃; for 10h;

DOI:10.1016/S0022-1139(00)82839-0

Reference yield: 54.0%

hexafluoroglutaric acid (376-73-8) → 1,3-dichlorohexafluoropropane (662-01-1)

Guidance literature:

With xenon difluoride; chlorine; In dichloromethane;

DOI:10.1021/jo00076a072

Reference yield: 53.0%

1,1,2,2,3,3-Hexafluoro-cyclopropane (931-91-9) → 1,3-dichlorohexafluoropropane (662-01-1)

Guidance literature:

With chlorine; at 155 ℃;

DOI:10.1021/jo030014y

upstream raw materials:

1-chloro-1,1,2,2,3,3-hexafluoropropane

1,1,3,3-tetrachloro-1,2,2,3-tetrafluoropropane

1,1,1,3,3,3-hexachloro-2,2-difluoro-propane

tetrachloro-1,2,2-trifluoro-1-iodo-propane

Downstream raw materials:

1-chloro-1,1,2,2,3,3-hexafluoropropane

perfluoropropyl chloride

Refernces

• 1、 Hauptschein et al.. "". . p. 848. Retrieved 1952.
• 2、 Yang, Zhen-Yu. "Preparation of highly fluorinated cyclopropanes and ring-opening reactions with halogens". . p. 4410 - 4416. Retrieved 2007/10/03.