(2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate

Base Information Edit

Chemical Name:(2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate
CAS No.:149690-12-0
Molecular Formula:C20H26ClNO2
Molecular Weight:347.885
Hs Code.:
Mol file:149690-12-0 .mol

Synonyms:(2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate;(2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate hydrochloride;(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic acid ethyl ester hydrochloride;(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic acid ethyl ester hydrochloride (1:1);(2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate HCl;LCZ696 Intermediate2;LCZ698;[1,1'-Biphenyl]-4-pentanoic acid, γ-amino-α-methyl-, ethyl ester, hydrochloride (1:1), (αR,γS)-

Suppliers and Price of (2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoicAcidEthylEsterHydrochloride
50mg
$ 95.00

Labseeker
(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoicacidethylesterhydrochloride 98
1kg
$ 21666.00

Crysdot
(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95+%
10g
$ 250.00

Crysdot
(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95+%
1g
$ 50.00

Crysdot
(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95+%
5g
$ 150.00

Crysdot
(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95+%
25g
$ 490.00

Chemenu
(2R,4S)-Ethyl5-([1,1''-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95+%
1000g
$ 1748.00

Ambeed
(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95%
100g
$ 1192.00

Ambeed
(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95%
25g
$ 404.00

Ambeed
(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95%
5g
$ 135.00

Total 107 raw suppliers

Chemical Property of (2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate Edit

Chemical Property:

PSA：52.32000
LogP:5.31500
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
Solubility.:DMSO (Slightly), Methanol (Slightly)

Purity/Quality:: (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoicAcidEthylEsterHydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride is used as a reagent in the synthesis of LCZ696, an angiotensin II receptor and neprilysin receptor dual inhibitor. (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride is also used as a reagent in the preparation of novel NEP inhibitor prodrugs for the treatment of hypertension and cardiovascular diseases.

Technology Process of (2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate

There total 47 articles about (2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%