methyl 2-cycloheptylacetate

Base Information

• Chemical Name: methyl 2-cycloheptylacetate
• CAS No.: 14224-70-5
• Molecular Formula: C10H18O2
• Molecular Weight: 170.25
• Mol file: 14224-70-5.mol

Synonyms:methyl 2-cycloheptylacetate

Chemical Property of methyl 2-cycloheptylacetate

Chemical Property:

• PSA: 26.30000
• LogP: 2.51990

Purity/Quality:

99% ^*data from raw suppliers

Methyl2-cycloheptylacetate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of methyl 2-cycloheptylacetate

There total 6 articles about methyl 2-cycloheptylacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.9%

methanol (67-56-1) + 2-cycloheptylacetic acid (4401-20-1) → methyl 2-cycloheptylacetate (14224-70-5)

Guidance literature:

With sulfuric acid; at 70 ℃; for 16h;

Reference yield: 85.0%

Cycloheptyl-methanesulfonyloxy-acetic acid methyl ester → methyl 2-cycloheptylacetate (14224-70-5)

Guidance literature:

With diphenyl diselenide; sodium perchlorate; diethyl malonate; In N,N-dimethyl-formamide; at 50 ℃; for 7.3h; electroreduction, 4.9 F mol^-1;

DOI:10.1246/bcsj.65.3200

Reference yield:

1-iodo-4-pentene (7766-48-5) → methyl 2-cycloheptylacetate (14224-70-5)

Guidance literature:

Multi-step reaction with 3 steps

1: 1.) NaH, n-BuLi

2: H⁺

3: 1.) acetone, 2.) p-TsOH / 1.) acetonitrile, irrad., 2.) reflux

With n-butyllithium; hydrogen cation; sodium hydride; toluene-4-sulfonic acid; acetone;

upstream raw materials:

methanol

2,2-Dimethyl-6-(5'-hexenyl)-1,3-dioxin-4-one

cis-3a,7a-Dihydro-indenon, cis-8,9-Dihydroindenon

1-iodo-4-pentene

Downstream raw materials:

2-cycloheptylacetaldehyde

2-cycloheptylethanol

Cycloheptyl-essigsaeure-amid

Refernces

• 1、 -. "BIARYL PYRAZOLES AS NRF2 REGULATORS". Page/Page column 154. . Retrieved 2017/08/01.
• 2、 Inokuchi, Tsutomu,Sugimoto, Tatsuya,Kusumoto, Masahiko,Torii, Sigeru. "Electroreductive Deoxygenation of Methanesulfonates of α-Hydroxy Esters via a Catalytic Selenation-Deselenation Sequence". . p. 3200 - 3202. Retrieved 2007/10/02.