1,7-bis(phenylcarbonyl)-4-oxa-1,7-diazaheptane

Base Information

• Chemical Name: 1,7-bis(phenylcarbonyl)-4-oxa-1,7-diazaheptane
• CAS No.: 105399-89-1
• Molecular Formula: C₁₈H₂₀N₂O₃
• Molecular Weight: 312.368
• Mol file: 105399-89-1.mol

Synonyms:1,7-bis(phenylcarbonyl)-4-oxa-1,7-diazaheptane

Chemical Property of 1,7-bis(phenylcarbonyl)-4-oxa-1,7-diazaheptane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,7-bis(phenylcarbonyl)-4-oxa-1,7-diazaheptane

There total 2 articles about 1,7-bis(phenylcarbonyl)-4-oxa-1,7-diazaheptane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

2,2'-diaminodiethyl ether (2752-17-2) + benzoyl chloride (98-88-4) → 1,7-bis(phenylcarbonyl)-4-oxa-1,7-diazaheptane (105399-89-1)

Guidance literature:

With triethylamine; In benzene; for 3h; Ambient temperature;

DOI:10.1021/jo00376a059

Reference yield: 85.0%

2-(2-aminoethoxy)ethanamine dihydrochloride (60792-79-2) + benzoyl chloride (98-88-4) → 1,7-bis(phenylcarbonyl)-4-oxa-1,7-diazaheptane (105399-89-1)

Guidance literature:

With sodium hydroxide; In dichloromethane; water; for 0.166667h; Ambient temperature;

DOI:10.1021/j100135a022

Reference yield: 94.0%

1,7-bis(phenylcarbonyl)-4-oxa-1,7-diazaheptane (105399-89-1) → 1,7-dibenzyl-4-oxa-1,7-diazaheptane (66582-25-0)

Guidance literature:

With borane-THF; for 72h; Ambient temperature;

DOI:10.1021/jo00376a059

upstream raw materials:

2,2'-diaminodiethyl ether

benzoyl chloride

2-(2-aminoethoxy)ethanamine dihydrochloride

Downstream raw materials:

1,7-dibenzyl-4-oxa-1,7-diazaheptane

10,16-dibenzyl-10,16-diaza-1,4,7,13-tetraoxacyclooctadecane

7,13-dibenzyl-7,13-diaza-1,4,10-trioxacyclopentadecane

Refernces

• 1、 Gatto, Vincent J.,Arnold, Kristin A.,Viscariello, Anthony M.,Miller, Steven R.,Morgan, Charles R.,Gokel, George W.. "Syntheses and Binding Properties of Bibracchial Lariat Ethers (BIBLEs): Survey of Synthetic Methods and Cation Selectivities". . p. 5373 - 5384. Retrieved 2007/10/02.