2-methoxycyclohexanone dimethyl acetal

Base Information

• Chemical Name: 2-methoxycyclohexanone dimethyl acetal
• CAS No.: 67820-35-3
• Molecular Formula: C₉H₁₈O₃
• Molecular Weight: 174.24
• Mol file: 67820-35-3.mol

Synonyms:2-methoxycyclohexanone dimethyl acetal

Chemical Property of 2-methoxycyclohexanone dimethyl acetal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of 2-methoxycyclohexanone dimethyl acetal

There total 10 articles about 2-methoxycyclohexanone dimethyl acetal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

2-methoxycyclohexanone (7429-44-9) + trimethyl orthoformate (149-73-5) → 2-methoxycyclohexanone dimethyl acetal (67820-35-3)

Guidance literature:

With toluene-4-sulfonic acid; In methanol; for 16h; Ambient temperature;

DOI:10.1021/ja00049a014

Reference yield: 85.0%

2-bromocyclohexanone (1056477-06-5,822-85-5) + methanol (67-56-1) → α-bromocyclohexanone dimethyl ketal (1728-17-2) + 2-methoxycyclohexanone dimethyl acetal (67820-35-3)

Guidance literature:

at 20 ℃; for 20h; Photolysis;

DOI:10.1246/bcsj.73.1645

Reference yield: 80.0%

methanol (67-56-1) + cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) + trimethyl orthoformate (149-73-5) → 2-methoxycyclohexanone dimethyl acetal (67820-35-3)

Guidance literature:

With ammonium cerium(IV) nitrate; iodine; for 8h; Heating;

DOI:10.1246/bcsj.70.421

upstream raw materials:

methanol

1-methoxy-cyclohex-1-ene

sodium methylate

2,2-dimethoxycyclohexanol

Downstream raw materials:

C₁₅H₂₈O₄Si

methyl 6,6-dimethoxyhexanoate

Refernces

• 1、 Ji, Shun-Jun,Horiuchi, C. Akira. "Photo-cleavage of carbon-carbon bond of α-iodocycloalkanones giving ω,ω-dialkoxyalkanoic ester in alcohol". . p. 1645 - 1652. Retrieved 2007/10/03.
• 2、 Adam, Waldemar,Prein, Michael,Richter, Markus J.. "Stereochemically defined cyclohexanediols through the regioselective ring-opening of silylated epoxy alcohols". . p. 1231 - 1234. Retrieved 2007/10/03.