3-methylphenyl formate

Base Information

• Chemical Name: 3-methylphenyl formate
• CAS No.: 1864-96-6
• Molecular Formula: C₈H₈O₂
• Molecular Weight: 136.15
• Mol file: 1864-96-6.mol

Synonyms:3-methylphenyl formate

Chemical Property of 3-methylphenyl formate

Chemical Property:

Purity/Quality:

Safty Information:

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• Hazard Codes: 

MSDS Files:

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Technology Process of 3-methylphenyl formate

There total 6 articles about 3-methylphenyl formate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

formic acid (64-18-6) + 3-methyl-phenol (108-39-4) → 3-methylphenyl formate (1864-96-6)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium acetate; acetic anhydride; at 20 ℃; for 12h; Inert atmosphere;

DOI:10.1002/cctc.201600165

Reference yield: 78.0%

sodium diformamide (18197-26-7) + 3-methyl-phenol (108-39-4) → 3-methylphenyl formate (1864-96-6)

Guidance literature:

sodium diformamide; With methanesulfonyl chloride; In acetonitrile; at 20 - 25 ℃; for 2h;

3-methyl-phenol; In acetonitrile; for 2h; Reflux;

DOI:10.1515/znb-2008-0414

Reference yield:

formic acid (64-18-6) + lithium formate (556-63-8) + toluene (108-88-3,15644-74-3,16713-13-6) → p-tolyl formate (1864-97-7) + 3-methylphenyl formate (1864-96-6) + o-methylphenyl formate (1864-95-5)

Guidance literature:

With CoO₄₀W₁₂^(5-)*16H₂O*5K⁽¹⁺⁾; In acetonitrile; Kinetics; Electrochemical reaction;

DOI:10.1039/d0sc04936k

upstream raw materials:

3-methyl-phenol

sodium diformamide

formic acid

formyl acetic anhydride

Downstream raw materials:

Dichlormethyl-m-tolylaether

3-methylphenyl benzoate

1-(difluoromethoxy)-3-methylbenzene

Refernces

• 1、 Jiang, Li-Bing,Li, Rui,Li, Hao-Peng,Qi, Xinxin,Wu, Xiao-Feng. "Palladium-Catalyzed Carbonylative Synthesis of Aryl Formates under Mild Conditions". . p. 1788 - 1791. Retrieved 2016/06/01.
• 2、 Chen, Guangwei,Leng, Yuting,Yang, Fan,Wang, Shiwei,Wu, Yangjie. "Palladacycle-catalyzed carbonylation of aryl iodides or bromides with aryl formates". . p. 1488 - 1494. Retrieved 2014/01/06.