1,2-bis(4-methylphenyl)-1,2-ethanediol

Base Information

• Chemical Name: 1,2-bis(4-methylphenyl)-1,2-ethanediol
• CAS No.: 5173-28-4
• Molecular Formula: C₁₆H₁₈O₂
• Molecular Weight: 242.318
• Mol file: 5173-28-4.mol

Synonyms:

Chemical Property of 1,2-bis(4-methylphenyl)-1,2-ethanediol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,2-bis(4-methylphenyl)-1,2-ethanediol

There total 59 articles about 1,2-bis(4-methylphenyl)-1,2-ethanediol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1,2-di(4-methylphenyl)-1,2-ethanedione (3457-48-5) → 1,2-di-p-tolylethane-1,2-diol (5173-28-4,5173-29-5,24133-59-3,66749-58-4,66768-19-2)

Guidance literature:

With sodium tetrahydroborate; In methanol; at 0 ℃; for 1h;

DOI:10.1021/ol802351r

Reference yield: 100.0%

4-methyl-benzaldehyde (104-87-0) → 1,2-di-p-tolylethane-1,2-diol (5173-28-4,5173-29-5,24133-59-3,66749-58-4,66768-19-2)

Guidance literature:

With aluminium; potassium hydroxide; In methanol; at 0 ℃; for 1h; Inert atmosphere;

DOI:10.1021/ol501012f

Reference yield: 99.0%

4,4'-dimethylbenzoin (1218-89-9) → 1,2-di-p-tolylethane-1,2-diol (5173-28-4,5173-29-5,24133-59-3,66749-58-4,66768-19-2)

Guidance literature:

With sodium tetrahydroborate; sodium hydrogen sulfate; In acetonitrile; at 20 ℃; for 0.0833333h;

DOI:10.1515/znb-2005-0417

upstream raw materials:

para-xylene

4-methyl-benzaldehyde

Glyoxal

para-methylphenylmagnesium bromide

Downstream raw materials:

1,2-bis(4-methylphenyl)-1,2-ethanediol

1,2-di(4-methylphenyl)-1,2-ethanedione

(R,R)-(+)-1,2-di(p-methylphenyl)ethane-1,2-diol

2,3-bis(4-methylphenyl)quinoxaline

Refernces

• 1、 Hernández-Ruiz, Raquel,Rubio-Presa, Rubén,Suárez-Pantiga, Samuel,Pedrosa, María R.,Fernández-Rodríguez, Manuel A.,Tapia, M. José,Sanz, Roberto. "Mo–Catalyzed One-Pot Synthesis of N-Polyheterocycles from Nitroarenes and Glycols with Recycling of the Waste Reduction Byproduct. Substituent-Tuned Photophysical Properties". supporting information. p. 13613 - 13623. Retrieved 2021/08/23.
• 2、 Wang, Xincan,Xie, Guanqun,Zhao, Yanfei,Zheng, Ke,Fang, Yanxiong,Wang, Xiaoxia. "Facile pinacol coupling of aliphatic ketones by Brook rearrangement in the presence of samarium species". supporting information. . Retrieved 2021/04/27.