Orally bioavailable

Synthesis Evaluation Antagonist Inhibitors Derivatives Optimization Antagonists Inhibitor Discovery Potent Efficacious Selective Allosteric Modulators Histamine H3 receptor Experimental Chemical compound Acute Myeloid Leukemia Imidazo[4,5-b]pyridine-based kinase inhibitors FLT3 Aurora kinase Preclinical development candidate Pyridazinone Phenethylamine Wake-promoting activity Interleukin-1 receptor-associate kinase-4 metabotropic glutamate subtype 5 (mGlu5) receptor 3-Fluoro-5-(5-pyridin-2-yl-2H-tetrazol-2-yl)phenyl-4-methylpyridine synaptic plasticity learning and memory pyridine-2-yl-2H-tetrazol-2-yl N-(3R,6S)-6 Calcitonin gene-related peptide receptor Migraine 2,3-difluorophenyl 2,2,2-trifluoroethyl Azepan-3-yl Imidazo[4,5-b]pyridin-1-yl Piperidine-1-carboxamide MK-0974 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide Apixaban BMS-562247 Blood coagulation factor Xa β-Arrestin Biased agonist CNS penetrant Neurotensin receptor 1 (NTR1) 3-(3-phenyl-3H-imidazo[4,5-b] pyridin-2-yl)pyridin-2-amines ATP-independent Akt inhibitors