112849-17-9 Usage
Description
(2E,4R)-4-[(1R,3aS,4E,7aR)-4-[(2E)-2-[(3S,5R)-3,5-Bis[[(tert-butyl)dimethylsilyl]oxy]-2-methylenecyclohexylidene]ethylidene]octahydro-7a-methyl-1H-inden-1-yl]-1-cyclopropyl-2-penten-1-one is a complex organic compound with a unique molecular structure. It is characterized by its white solid appearance and is an intermediate in the preparation of Vitamin D analogs.
Uses
Used in Pharmaceutical Industry:
(2E,4R)-4-[(1R,3aS,4E,7aR)-4-[(2E)-2-[(3S,5R)-3,5-Bis[[(tert-butyl)dimethylsilyl]oxy]-2-methylenecyclohexylidene]ethylidene]octahydro-7a-methyl-1H-inden-1-yl]-1-cyclopropyl-2-penten-1-one is used as an intermediate in the synthesis of Vitamin D analogs, which have potential applications in the development of drugs for various health conditions.
Used in Chemical Research:
As a complex organic compound, (2E,4R)-4-[(1R,3aS,4E,7aR)-4-[(2E)-2-[(3S,5R)-3,5-Bis[[(tert-butyl)dimethylsilyl]oxy]-2-methylenecyclohexylidene]ethylidene]octahydro-7a-methyl-1H-inden-1-yl]-1-cyclopropyl-2-penten-1-one can also be used in chemical research for studying its properties, reactivity, and potential applications in various chemical processes.
Check Digit Verification of cas no
The CAS Registry Mumber 112849-17-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,2,8,4 and 9 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 112849-17:
(8*1)+(7*1)+(6*2)+(5*8)+(4*4)+(3*9)+(2*1)+(1*7)=119
119 % 10 = 9
So 112849-17-9 is a valid CAS Registry Number.
InChI:InChI=1/C39H66O3Si2/c1-27(16-23-35(40)30-18-19-30)33-21-22-34-29(15-14-24-39(33,34)9)17-20-31-25-32(41-43(10,11)37(3,4)5)26-36(28(31)2)42-44(12,13)38(6,7)8/h16-17,20,23,27,30,32-34,36H,2,14-15,18-19,21-22,24-26H2,1,3-13H3/b23-16+,29-17+,31-20+/t27-,32-,33-,34+,36+,39-/m1/s1
112849-17-9Relevant articles and documents
Efficient synthesis of novel oxime analogues of the hormone 1α, 25-dihydroxyvitamin D3Paper
Li, Hongliang,Fang, Zhijie,Dai, Huanran,Zhang, Hengrui,Liu, Yanan
, p. 368 - 372 (2015/08/18)
Calcitriol analogues which contained an oxime in the side chain were synthesised in five steps from an intermediate 22-nor Ketone. The key intermediate enones were synthesised by the Wittig-Horner olefination and Wittig olefination respectively. Reduction
STEREOSELECTIVE SYNTHESIS OF VITAMIN D ANALOGUES
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Page/Page column 22-23, (2008/06/13)
The present invention relates to intermediates useful for the synthesis of calcipotriol or calcipotriol monohydrate, to methods of producing said intermediates, and to methods of stereoselectively reducing said intermediates.