1270019-95-8Relevant articles and documents
Preparation method of 3-substituted-5-aminopiperidine with protecting group
-
, (2020/12/30)
The invention provides a preparation method of 3-substituted-5-aminopiperidine with a protecting group, and particularly provides a preparation method of 3-substituted-5-aminopiperidine with a protecting group, which has the advantages of low cost and easily available raw materials and reaction reagents.
POLYCYCLIC TLR7/8 ANTAGONISTS AND USE THEREOF IN THE TREATMENT OF IMMUNE DISORDERS
-
, (2017/07/06)
The present invention relates to compounds of Formula (I) and pharmaceutically acceptable compositions thereof, useful as toll-like receptor 7/8 (TLR7/8) antagonists. In Formula (I), Ring A is aryl or heteroaryl; Ring B is aryl or heteroary; and X is C(R4)2, O, NR4, S, S(R4), or S(R4)2.
BICYCLIC HETEROAROMATIC CARBOXAMIDE COMPOUNDS USEFUL AS PIM KINASE INHIBITORS
-
, (2016/02/26)
The present disclosure describes bicyclic heteroaromatic carboxamide derivatives of formula (I), as well as their compositions and methods of use. The compounds inhibit the activity of the Pim kinases, and are useful in the treatment of diseases related to the activity of Pim kinases including, e.g., cancer and other diseases.