2089-32-9

Basic information

• Product Name: (1E)-1-(4-ethylphenyl)ethanone oxime
• Synonyms: 1-(4-Ethylphenyl)ethanone oxime; Ethanone, 1-(4-ethylphenyl)-, oxime (9CI); ethanone, 1-(4-ethylphenyl)-, oxime, (1E)-
• CAS NO: 2089-32-9
• Molecular Formula: C₁₀H₁₃NO
• Molecular Weight: 163.2163
• Mol File: 2089-32-9.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 272.9°C at 760 mmHg
• Flash Point: 159.4°C
• Density: 0.98g/cm³
• Vapor Pressure: 0.00289mmHg at 25°C
• Refractive Index: 1.512
• CAS DataBase Reference: (1E)-1-(4-ethylphenyl)ethanone oxime(CAS DataBase Reference)
• NIST Chemistry Reference: (1E)-1-(4-ethylphenyl)ethanone oxime(2089-32-9)
• EPA Substance Registry System: (1E)-1-(4-ethylphenyl)ethanone oxime(2089-32-9)

Safety Data

• Hazardous Substances Data: 2089-32-9(Hazardous Substances Data)

Usage

Description

(1E)-1-(4-ethylphenyl)ethanone oxime is a ketoxime, a type of organic compound with the molecular formula C10H13NO. It contains a nitroso group (-NO) bonded to a carbon atom and is commonly used as a reagent in chemical reactions to form oximes, which are important intermediates in organic synthesis.

Uses

Used in Organic Synthesis:
(1E)-1-(4-ethylphenyl)ethanone oxime is used as a reagent for forming oximes, which are important intermediates in organic synthesis. Its versatility in forming oximes makes it a valuable compound in the synthesis of various organic compounds.
Used in Pharmaceutical Industry:
(1E)-1-(4-ethylphenyl)ethanone oxime is used as a precursor for the synthesis of various pharmaceuticals and biologically active compounds. Its potential applications in the pharmaceutical industry make it a promising compound for the development of new drugs and therapeutic agents.
Used in Chemical Manufacturing Processes:
(1E)-1-(4-ethylphenyl)ethanone oxime may have some industrial uses as a reagent in chemical manufacturing processes. Its ability to form oximes can be utilized in various chemical processes, contributing to the production of different chemical products.

Upstream product

• 937-30-4 4-ethylacetophenone 

Downstream Products

• 64222-38-4 1-Vinyl-2-(p-ethylphenyl)pyrrole 
• 88054-90-4 2-(p-Ethylphenyl)pyrrole 
• 3663-34-1 N-(4-ethylphenyl)acetamide 
• 64128-35-4 C₂₃H₂₉NO₃ 
• 121505-64-4 1-(4-Ethyl-phenyl)-ethanone O-{2-[1-(4-ethyl-phenyl)-eth-(E)-ylideneaminooxy]-ethyl}-oxime 

Relevant articles and documents

Rhodium(iii)-catalyzed asymmetric [4+1] spiroannulations of: O -pivaloyl oximes with α-diazo compounds

Chiral RhIII catalysts can catalyze the asymmetric [4+1] spiroannulation of O-pivaloyl oximes with α-diazo homophthalimides under redox-neutral and acid/base-neutral conditions, leading to formation of chiral spirocyclic imines as a result of C-H activation and N-O cleavage. The reaction proceeded with high efficiency and features broad substrate scope, mild reaction conditions, and high to excellent enantioselectivities. This journal is

Rhodium(III)-Catalyzed Annulation of Acetophenone O-Acetyl Oximes with Allenoates through Arene C-H Activation: An Access to Isoquinolines

Rhodium(III)-catalyzed annulation of acetophenone O-acetyl oximes with allenoates was achieved, affording isoquinolines in good to excellent yields with high regioselectivities under redox-neutral conditions. Allenoates acted as the C2 synthons in the annulation reaction. The present synthetic methodology features good functional group tolerance and avoids metal salts as the external oxidants. The proposed mechanism suggests that the reaction proceeds through arene C-H activation, allene insertion, and C-N coupling.

Copper-catalyzed synthesis of thiazol-2-yl ethers from oxime acetates and xanthates under redox-neutral conditions

A novel copper-catalyzed annulation of oxime acetates and xanthates for the synthesis of thiazol-2-yl ethers with remarkable regioselectivity has been developed. Various oxime acetates, whether derived from aryl ketones or alkyl ketones, or natural product cores are suitable for this conversion. Unique dihydrothiazoles were also obtained when both reaction sites were methine. Mechanistic studies indicated that imino copper(iii) intermediates were involved. In addition, this protocol proceeded under redox-neutral conditions and did not require additives or ligands.