21210-43-5 Usage
Description
(S)-(+)-Methyl mandelate, also known as Methyl (S)-(+)-Mandelate, is an optically active building block with the CAS number 21210-43-5. It is a white crystalline powder that is useful in organic synthesis due to its unique chemical properties.
Uses
1. Used in Organic Synthesis:
(S)-(+)-Methyl mandelate is used as a building block for the synthesis of various organic compounds. Its optical activity makes it a valuable component in the creation of chiral molecules, which are essential in the pharmaceutical and chemical industries.
2. Used in Pharmaceutical Industry:
(S)-(+)-Methyl mandelate is used as an intermediate in the preparation of specific pharmaceutical compounds. For example, it may be used in the synthesis of (S)-(-)2-hydroxy-1,2,2-triphenylethyl acetate and (α′S)-α′-methoxycarbonylbenzyl (2S,4R)-(+)-1,2,4,5-tetrahydro-4-methyl-7,8-methylenedioxy-5-oxo-3-benzothiepin-2-carboxylate. These compounds have potential applications in the development of new drugs and therapies.
3. Used in Chemical Research:
(S)-(+)-Methyl mandelate is also utilized in chemical research for studying the properties and reactions of optically active compounds. Its unique structure allows researchers to explore various chemical pathways and mechanisms, contributing to the advancement of knowledge in the field of chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 21210-43-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,2,1 and 0 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 21210-43:
(7*2)+(6*1)+(5*2)+(4*1)+(3*0)+(2*4)+(1*3)=45
45 % 10 = 5
So 21210-43-5 is a valid CAS Registry Number.
InChI:InChI=1/C9H10O3/c1-12-9(11)8(10)7-5-3-2-4-6-7/h2-6,8,10H,1H3/t8-/m0/s1
21210-43-5Relevant articles and documents
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Peters,H.M. et al.
, p. 4245 - 4250 (1968)
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Catalytic enantioselective O-H insertion reactions
Maier, Thomas C.,Fu, Gregory C.
, p. 4594 - 4595 (2006)
The first effective method for catalytic enantioselective insertions into O-H bonds has been developed. Specifically, a copper/bisazaferrocene catalyst couples alcohols such as 2-trimethylsilylethanol with α-aryl-α-diazo esters in high yield and good ee.
Total Synthesis of (-)-Disorazole C1
Lizzadro, Luca,Spie?, Oliver,Schinzer, Dieter
supporting information, p. 4543 - 4547 (2021/06/28)
Disorazoles represent a powerful class of highly potent antitubulin natural products isolated from myxobacteria. Herein, we describe a scalable and robust synthesis of (-)-disorazole C1 with high stereoselectivity, featuring quite simple reaction conditio
1,3-mandelic acid thioether derivative containing '4 - R/S - oxadiazole' structure and application thereof
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Paragraph 0021-0024; 0025, (2021/10/13)
1,3 Mandelic acid thioether compound containing the structure of '4 - R/S - oxadiazole' is characterized in that the structure is as shown in the general formula (In / IIn) and (In In-flight R1 A is H or Cl, R. 2 For linear alkanes C