22771-99-9 Usage
Description
4-(4-Chlorophenylsulfonyl)Morpholine, 97% is a chemical compound with a molecular formula of C10H11ClNO3S and a molecular weight of 261.72 g/mol. It is a white to off-white crystalline solid with a purity of 97%, and is soluble in organic solvents such as methanol and ethanol. 4-(4-Chlorophenylsulfonyl)Morpholine, 97% is known for its ability to react with a variety of nucleophiles and electrophiles, making it a versatile reagent in organic synthesis.
Uses
Used in Pharmaceutical Industry:
4-(4-Chlorophenylsulfonyl)Morpholine, 97% is used as a building block for the synthesis of pharmaceuticals. Its reactivity with nucleophiles and electrophiles allows for the creation of a wide range of drug molecules, contributing to the development of new medications.
Used in Agrochemical Industry:
In the agrochemical industry, 4-(4-Chlorophenylsulfonyl)Morpholine, 97% serves as a key component in the synthesis of various agrochemicals. Its versatility in reactions enables the production of effective compounds for crop protection and other agricultural applications.
Used in Fine Chemicals Synthesis:
4-(4-Chlorophenylsulfonyl)Morpholine, 97% is utilized as a reagent in the synthesis of fine chemicals. Its ability to participate in numerous chemical reactions makes it a valuable asset in the production of specialty chemicals for various industries.
Used as a Crosslinking Agent in Polymer Materials:
4-(4-Chlorophenylsulfonyl)Morpholine, 97% is also used as a crosslinking agent in the preparation of polymer materials. This application enhances the properties of polymers, such as their strength, stability, and durability, making them suitable for a broader range of uses.
Check Digit Verification of cas no
The CAS Registry Mumber 22771-99-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,7,7 and 1 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 22771-99:
(7*2)+(6*2)+(5*7)+(4*7)+(3*1)+(2*9)+(1*9)=119
119 % 10 = 9
So 22771-99-9 is a valid CAS Registry Number.
InChI:InChI=1/C10H12ClNO3S/c11-9-1-3-10(4-2-9)16(13,14)12-5-7-15-8-6-12/h1-4H,5-8H2
22771-99-9Relevant articles and documents
S(vi) in three-component sulfonamide synthesis: Use of sulfuric chloride as a linchpin in palladium-catalyzed Suzuki-Miyaura coupling
Wang, Xuefeng,Yang, Min,Ye, Shengqing,Kuang, Yunyan,Wu, Jie
, p. 6437 - 6441 (2021/05/19)
Sulfuric chloride is used as the source of the -SO2- group in a palladium-catalyzed three-component synthesis of sulfonamides. Suzuki-Miyaura coupling between the in situ generated sulfamoyl chlorides and boronic acids gives rise to diverse sulfonamides in moderate to high yields with excellent reaction selectivity. Although this transformation is not workable for primary amines or anilines, the results show high functional group tolerance. With the solving of the desulfonylation problem and utilization of cheap and easily accessible sulfuric chloride as the source of sulfur dioxide, redox-neutral three-component synthesis of sulfonamides is first achieved. This journal is
Efficient and Practical Synthesis of Sulfonamides Utilizing SO2 Gas Generated on Demand
Chung Leung, Gulice Yiu,Ramalingam, Balamurugan,Loh, Gabriel,Chen, Anqi
, p. 546 - 554 (2020/04/22)
A simple and practical protocol was developed for the synthesis of sulfonamides by reacting organometallic reagents with SO2 gas generated on demand. SO2 was generated from readily available reagents safely in a highly contained and controlled fashion. The protocol allows the synthesis of sulfonamides without using either atom-inefficient SO2 surrogates or a SO2 cylinder that requires stringent storage regulations in the laboratory. The protocol was successfully applied to the synthesis of sildenafil.
Cu-catalyzed aerobic oxidative synthesis of sulfonamides from sulfonyl hydrazides and amines
Chung, Sohyun,Kim, Jinho
supporting information, p. 792 - 795 (2019/02/16)
An environmentally friendly route for sulfonamides has been developed. The oxidative coupling of sulfonyl hydrazides and amines was catalyzed by CuBr2 to produce various sulfonamides with the water and nitrogen gas as byproducts. Preliminary experiments revealed that the sulfonyl radical is likely to be involved in the reaction mechanism.