2907-85-9 Usage
Description
(2-Oxotetrahydrofuran-3-yl)phosphonic acid diethyl ester is a chemical compound that is commonly used as a reagent in organic synthesis. It is a diethyl ester derivative of (2-oxotetrahydrofuran-3-yl)phosphonic acid, and it possesses a phosphonic acid functional group, making it useful in the formation of phosphonate esters. (2-Oxotetrahydrofuran-3-yl)phosphonic acid diethyl ester is known for its potential application in the development of pharmaceuticals, agrochemicals, and materials science, due to its versatile reactivity and ability to participate in various chemical reactions. Additionally, it has been studied for its potential as a ligand in coordination chemistry due to the presence of the phosphonic acid group.
Uses
Used in Pharmaceutical Industry:
(2-Oxotetrahydrofuran-3-yl)phosphonic acid diethyl ester is used as a reagent for the synthesis of pharmaceuticals, due to its versatile reactivity and ability to participate in various chemical reactions.
Used in Agrochemical Industry:
(2-Oxotetrahydrofuran-3-yl)phosphonic acid diethyl ester is used as a reagent for the synthesis of agrochemicals, due to its versatile reactivity and ability to participate in various chemical reactions.
Used in Materials Science:
(2-Oxotetrahydrofuran-3-yl)phosphonic acid diethyl ester is used as a reagent for the synthesis of materials, due to its versatile reactivity and ability to participate in various chemical reactions.
Used in Coordination Chemistry:
(2-Oxotetrahydrofuran-3-yl)phosphonic acid diethyl ester is used as a ligand in coordination chemistry, due to the presence of the phosphonic acid group.
Check Digit Verification of cas no
The CAS Registry Mumber 2907-85-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,9,0 and 7 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 2907-85:
(6*2)+(5*9)+(4*0)+(3*7)+(2*8)+(1*5)=99
99 % 10 = 9
So 2907-85-9 is a valid CAS Registry Number.
InChI:InChI=1/C8H15O5P/c1-3-12-14(10,13-4-2)7-5-6-11-8(7)9/h7H,3-6H2,1-2H3
2907-85-9Relevant articles and documents
Stereocontrol in Horner-Wadsworth-Emmons Condensations of α-Phosphono Lactones with Aldehydes: A Synthesis of Integerrinecic Acid and Senecic Acid Lactones
Lee, Koo,Jackson, John A.,Wiemer, David F.
, p. 5967 - 5971 (1993)
The Horner-Wadsworth-Emmons condensations of α-phosphono lactones were investigated under a variety of conditions.Upon treatment with KHMDS and 18-crown-6 in THF, condensations of the five-membered ring phosphono lactones 7a and 8 with propionaldehyde afforded the E olefins cleanly.In contrast, these phosphonates gave predominantly the Z olefins upon treatment with propionaldehyde, K2CO3 and 18-crown-6 in THF.A similar, though somewhat less-pronounced trend was observed with the six-membered ring phosphono lactone 9a.However, in its condensation with acetaldehyde the more functionalized phosphono lactone 4 gave the best E selectivity (ca. 9:1) when DBU/CH3CN was used, providing the methyl ester of integerrinecic acid lactone (5) in 77percent isolated yield.When K2CO3/18-crown-6/toluene was employed in a parallel reaction, only slight selectivity for the Z isomer was observed, but the methyl ester of senecic acid lactone (6) still was obtained in 43-46percent yield from the product mixture.
Novel synthesis of physovenine and physostigmine analogs
Wang,Alluri,Nikogosyan,Decarlo,Monteiro,Mabagos,Feng,White,Bartolini,Andrisano,Zhang,Ganguly
, p. 3046 - 3049 (2016/07/06)
This Letter describes a versatile synthetic approach to prepare physovenine and physostigmine analogs. A series of analogs were synthesized and evaluated for cholinesterase inhibition activities, including human acetylcholinesterase (AChE) and butyrylchol
7-AMINO ALKYLIDENYL-HETEROCYCLIC QUINOLONES AND NAPHTHYRIDONES
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Page/Page column 51, (2008/06/13)
The present invention relates to compounds having a structure according to Formula I wherein n, m, z, R, R2, R3, R4, R5, R6, A, E, X, Y a and b are as defined above; or an optical isomer, diastereomer or enantiomer thereof; a pharmaceutically acceptable s