31332-88-4 Usage
Description
Benzyl (2-oxotetrahydrofuran-3-yl)carbamate is a synthetic compound that features a benzyl group attached to a carbamate group and a 2-oxotetrahydrofuran-3-yl group. It is recognized for its role in organic synthesis, particularly as a protecting group for amines and alcohols, and as a precursor in the production of pharmaceuticals and agricultural chemicals. Its structural attributes and potential to engage with specific biological pathways have positioned benzyl (2-oxotetrahydrofuran-3-yl)carbamate as a promising candidate in medicinal chemistry for the development of therapeutic agents to address a range of diseases and disorders.
Uses
Used in Organic Synthesis:
Benzyl (2-oxotetrahydrofuran-3-yl)carbamate serves as a protecting group for amines and alcohols during organic synthesis processes. This function is crucial for preventing unwanted reactions at these functional groups, thereby allowing chemists to selectively modify other parts of a molecule.
Used in Pharmaceutical Development:
As a precursor, benzyl (2-oxotetrahydrofuran-3-yl)carbamate is instrumental in the preparation of various pharmaceuticals. Its structural components can be manipulated to create new drug molecules with potential therapeutic benefits.
Used in Agricultural Chemical Production:
benzyl (2-oxotetrahydrofuran-3-yl)carbamate also plays a role in the creation of agricultural chemicals, where it may be used as a starting material or an intermediate in the synthesis of pesticides, herbicides, or other agrochemicals.
Used in Medicinal Chemistry Research:
Benzyl (2-oxotetrahydrofuran-3-yl)carbamate is explored in medicinal chemistry as a potential drug candidate. Its capacity to target specific biological pathways makes it a valuable subject for research aimed at developing treatments for various diseases and disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 31332-88-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,1,3,3 and 2 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 31332-88:
(7*3)+(6*1)+(5*3)+(4*3)+(3*2)+(2*8)+(1*8)=84
84 % 10 = 4
So 31332-88-4 is a valid CAS Registry Number.
31332-88-4Relevant articles and documents
ETHYNYLBENZENE DERIVATIVES
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Page/Page column 45, (2012/03/26)
Disclosed are compounds of formulae (I), (II), and (II)I: and pharmaceutically acceptable salts thereof, wherein the variables, R, R1, R2, R3, R101, L, D, Q, Y, X, and Z are defined herein. These compounds are useful for treating Gram-negative bacteria infections.
Synthesis and in vitro enzyme activity of aza, oxa and thia derivatives of bacterial cell wall biosynthesis intermediates
Cox,Wang
, p. 2022 - 2034 (2007/10/03)
Mechanism based inhibitors of diaminopimelate aminotransferase (DAP-AT) were designed using knowledge of its substrate specificity and mechanism. Synthesis of thiolester and amide substrate analogues was achieved prior to in vitro inhibition studies, but ester analogues proved too unstable to isolate. Thia substrate analogues showed no inhibitory properties, but the aza substrate analogue 12a showed reversible inhibition vs. DAP-AT and time dependent inhibition in the absence of the natural substrate 4. Substrate analogue 12a is thefirst example of an amide inhibitor of PLP dependent enzymes. Antibiotic properties of 12a were also briefly assessed.
New synthetic routes to α-amino acids and γ-oxygenated α-amino acids. Reductive denitration and oxidative transformations of γ-nitro-α-amino acids
Crossley, Maxwell J.,Fung, Yik M.,Kyriakopoulos, Efstathia,Potter, Jeffrey J.
, p. 1123 - 1130 (2007/10/03)
Transformation of γ-nitro-α-amino acid derivatives into α-amino acids by reductive denitration, into the γ-oxo-α-amino acids by ozonolysis of the corresponding amino acid ester nitronate derivatives, and into γ-hydroxy-α-amino acid derivatives by subsequent reduction of the oxo functionality, can be achieved in good yields. As the γ-nitro-α-amino acid derivatives are prepared from N,O-protected dehydroalanines derivable from the corresponding alanine, serine and cysteine derivatives by specific routes, the overall procedures provide a means for selective conversion of these simple α-amino acids into more complex ones.
