36597-09-8Relevant articles and documents
Single-Flask Multicomponent Palladium-Catalyzed α,γ-Coupling of Ketone Enolates: Facile Preparation of Complex Carbon Scaffolds
Grigalunas, Michael,Norrby, Per-Ola,Wiest, Olaf,Helquist, Paul
, p. 11822 - 11825 (2015)
A three-component palladium-catalyzed reaction sequence has been developed in which γ-substituted α,β-unsaturated products are obtained in a single flask by an α-alkenylation with either a subsequent γ-alkenylation or γ-arylation of a ketone enolate. Coup
Iron-Catalyzed Synthesis of Dihydronaphthalenones from Aromatic Oxime Esters
Zhang, Youcan,Yin, Zhiping,Wu, Xiao-Feng
supporting information, p. 3223 - 3227 (2019/05/10)
Herein, a convenient procedure on iron-catalyzed radical-mediated synthesis of dihydronaphthalenones from oxime esters has been developed. By using iron salt as a green and inexpensive catalyst, various α-aryl oxime esters were transformed into the corresponding dihydronaphthalenones in moderate to good yields with high chemo-selectivities. The reaction proceeds via 1,5-hydrogen atom transfer and then intramolecular radical cyclization sequence. (Figure presented.).
Palladium-catalyzed alkenylation of ketone enolates under mild conditions
Grigalunas, Michael,Ankner, Tobias,Norrby, Per-Ola,Wiest, Olaf,Helquist, Paul
supporting information, p. 3970 - 3973 (2014/08/18)
A protocol for a mild, catalytic, intermolecular alkenylation of ketone enolates has been developed using a Pd/Q-Phos catalyst. Efficient intermolecular coupling of a variety of ketones with alkenyl bromides was achieved with a slight excess of LiHMDS and temperatures down to 0 °C.