3704-26-5 Usage
Description
1-(3,4,5-Trimethoxybenzoyl)piperidine, also known as TMBP, is a chemical compound with a molecular formula C16H23NO4. It is a piperidine derivative featuring a benzoyl group substituted with three methoxy groups. TMBP is a white to off-white solid that is soluble in organic solvents. It is commonly utilized in organic synthesis and medicinal chemistry as a building block for the synthesis of various pharmaceuticals and bioactive compounds. TMBP has also been investigated for its potential pharmacological effects, including its use as an anticonvulsant and a potential treatment for neurodegenerative diseases.
Uses
Used in Pharmaceutical Synthesis:
1-(3,4,5-Trimethoxybenzoyl)piperidine is used as a building block for the synthesis of various pharmaceuticals and bioactive compounds. Its unique chemical structure allows for the creation of a wide range of molecules with potential therapeutic applications.
Used in Medicinal Chemistry:
1-(3,4,5-Trimethoxybenzoyl)piperidine is used as a key intermediate in the development of new drugs, particularly those targeting the central nervous system. Its structural versatility makes it a valuable component in the design of novel therapeutic agents.
Used in Organic Synthesis:
1-(3,4,5-Trimethoxybenzoyl)piperidine is used as a versatile reagent in organic synthesis, enabling the creation of a diverse array of chemical products with potential applications in various industries.
Used in Neurodegenerative Disease Research:
1-(3,4,5-Trimethoxybenzoyl)piperidine is used as a potential treatment for neurodegenerative diseases due to its pharmacological effects. Its study contributes to the understanding of disease mechanisms and the development of new therapeutic strategies.
Used in Anticonvulsant Drug Development:
1-(3,4,5-Trimethoxybenzoyl)piperidine is used in the development of anticonvulsant drugs, offering a promising avenue for the treatment of epilepsy and other seizure disorders. Its potential to modulate neuronal activity makes it a valuable candidate for further research and development in this area.
Check Digit Verification of cas no
The CAS Registry Mumber 3704-26-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,7,0 and 4 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 3704-26:
(6*3)+(5*7)+(4*0)+(3*4)+(2*2)+(1*6)=75
75 % 10 = 5
So 3704-26-5 is a valid CAS Registry Number.
InChI:InChI=1/C15H21NO4/c1-18-12-9-11(10-13(19-2)14(12)20-3)15(17)16-7-5-4-6-8-16/h9-10H,4-8H2,1-3H3
3704-26-5Relevant articles and documents
Direct Synthesis of Enamides via Electrophilic Activation of Amides
Berger, Martin,Kaiser, Daniel,Maulide, Nuno,Spie?, Philipp
supporting information, p. 10524 - 10529 (2021/07/28)
A novel, one-step N-dehydrogenation of amides to enamides is reported. This reaction employs the unlikely combination of LiHMDS and triflic anhydride, which serves as both the electrophilic activator and the oxidant, and is characterized by its simple setup and broad substrate scope. The synthetic utility of the formed enamides was readily demonstrated in a range of downstream transformations.
N2 extrusion and co insertion: A novel palladium-catalyzed carbonylative transformation of aryltriazenes
Li, Wanfang,Wu, Xiao-Feng
, p. 1910 - 1913 (2015/04/27)
A novel procedure for the replacement of N2 with CO of aryltriazenes has been developed. Aryltriazenes were converted to the corresponding arylamides catalyzed by 1 mol % of PdCl2/P(o-Tol)3 under CO pressure. In this process, aryldiazonium salts were generated in the presence of 40 mol % of MeSO3H. Nitrogen was released from the substrates and CO formally inserted. Aryl bromides, iodides, alkynes, and free hydroxyl groups can be tolerated in this transformation.
