4265-27-4Relevant articles and documents
Karakhanov et al.
, (1971)
PALLADIUM ACYCLIC DIAMINOCARBENE COMPLEXES AS PRECATALYSTS FOR HIYAMA COUPLING AND THE TANDEM ONE-POT FLUORIDE FREE HIYAMA COUPLING/CYCLIZATION FOR THE SYNTHESIS OF BIOLOGICALLY RELEVANT
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Paragraph 0108; 0109; 0114-0115, (2020/05/06)
The present invention provides Acyclic diaminocarbene complex of formula (I): Wherein, M is palladium; X is monoanionic ligand selected from Cl, Br or I; Where R1 is different from R2; R1 is selected from the group consisting of alkyl or aryl, each of which have 4 to 20 carbon atoms, and may optionally contain one or more heteroatoms; R2 is selected from the group consisting of alkyl, or aryl each of which have 4 to 20 carbon atoms, and may optionally contain one or more heteroatoms. The said palladium diamino carbine complex of the present invention are particularly useful as catalyst from Hiyama cross-coupling reaction.
A 2 - substituted benzofuran compound of the catalytic synthesis method
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Paragraph 0016; 0017; 0018, (2019/05/22)
The invention discloses a 2 - substituted benzofuran compound of the catalytic synthesis method, comprises the following steps: normal temperature and pressure, the 2 - alkynyl substituted phenol dissolved in acetonitrile, wherein the 2 - alkynyl substituted phenol with acetonitrile molar volume ratio of 1: 1mmol/mL, to obtain 2 - alkynyl substituted phenol acetonitrile solution; and then to the acetonitrile solution in adding cuprous chloride and cesium carbonate, wherein the cuprous chloride and cesium carbonate of respectively the molar consumption of 2 - alkynyl-substituted phenol mole amount of 5%; after, room temperature stirring 6 hours, produced by the reaction of 2 - substituted benzofuran compound. The invention 2 - substituted benzofuran compound of the catalytic method for synthesis of low cost, high yield, its preparation 1 g of 2 - substituted benzofuran compounds required the cost of the catalyst the prior by iridium catalyst is a catalyst of the synthetic method has lowered 2 orders of magnitude, to improve the yield of the 88.5 - 95.8%.