52565-57-8

Basic information

• Product Name: 4-Phenylpyridine-2-carboxylic acid ethyl ester
• Synonyms: 4-Phenylpyridine-2-carboxylic acid ethyl ester;ethyl 4-phenylpicolinate
• CAS NO: 52565-57-8
• Molecular Formula: C₁₄H₁₃NO₂
• Molecular Weight: 227.25852
• Mol File: 52565-57-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 359.54 °C at 760 mmHg
• Flash Point: 171.244 °C
• Appearance: /
• Density: 1.123 g/cm³
• CAS DataBase Reference: 4-Phenylpyridine-2-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Phenylpyridine-2-carboxylic acid ethyl ester(52565-57-8)
• EPA Substance Registry System: 4-Phenylpyridine-2-carboxylic acid ethyl ester(52565-57-8)

Safety Data

• Hazardous Substances Data: 52565-57-8(Hazardous Substances Data)

Usage

General Description

4-Phenylpyridine-2-carboxylic acid ethyl ester, also known as ethyl 4-phenyl-2-pyridinecarboxylate, is a chemical compound with the molecular formula C13H13NO2. It is an ethyl ester derivative of 4-phenylpyridine-2-carboxylic acid and is commonly used in the pharmaceutical industry as an intermediate in the synthesis of various pharmaceutical drugs. It is also used as a reagent in organic synthesis and as a building block in the production of other chemical compounds. It is a yellow to light brown solid with a characteristic odor and is typically stored and handled in accordance with standard chemical safety procedures.

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Downstream Products

• 52565-58-9 1-(4-phenylpyridin-2-yl)ethan-1-one 

Relevant articles and documents

Visible-Light Photoredox-Catalyzed Formal [5 + 1] Cycloaddition of N-Tosyl Vinylaziridines with Difluoroalkyl Halides

A visible-light photoredox-catalyzed formal [5 + 1] cycloaddition of N-tosyl vinylaziridines with difluoroalkyl halides as unique C1 synthons was developed. The procedure provides an efficient and practical method to synthesize diverse pyridines in moderate to good yields. The reaction underwent a radical-initiated kinetically controlled ring-opening of vinylaziridines and involved a key α,β-unsaturated imine intermediate, followed by an E2 elimination, a 6πelectrocyclization, and defluorinated aromatization.

2-substituted piperidines, pyrrolidines and hexahydro-1H-azepines promote release of growth hormone

The present invention is directed to certain piperidine, pyrrolidine, and hexahydro-1H-azepine compounds of the general structural formula: STR1 wherein R1, R3, R4, R5, A, W, X, Y, and n axe as defined herein. T