612-15-7Relevant articles and documents
Functionalized styrene synthesis via palladium-catalyzed C[sbnd]C cleavage of aryl ketones
Zhang, Xu,Wang, Zhen-Yu,Wang, Xing,Xu, Hui,Dai, Hui-Xiong
, (2022/03/31)
We report herein the synthesis of functionalized styrenes via palladium-catalyzed Suzuki–Miyaura cross-coupling reaction between aryl ketone derivatives and potassium vinyltrifluoroborate. The employment of pyridine-oxazoline ligand was the key to the cleavage of unstrained C[sbnd]C bond. A variety of functional groups and biologically important moleculars were well tolerated. The orthogonal Suzuki–Miyaura coupling demonstrated the synthetic practicability.
Application of tungsten oxide supported monatomic catalyst in preparation of aromatic compound by hydrogenolysis of lignin
-
Paragraph 0044-0051, (2021/05/22)
The invention provides application of a tungsten oxide supported monatomic catalyst in preparation of aromatic compounds by hydrogenolysis of lignin. According to the method, various beta-O-4 model molecules, organic lignin, lignosulfonate and alkali lignin are taken as raw materials, and high-selectivity cracking of aryl ether bonds is realized in a hydrogen atmosphere at the temperature of 150-240 DEG C and the pressure of 0.7-3.0 MPa to obtain the aromatic compound. Compared with the prior art, the method has the advantages that when renewable natural biomass is used as the raw material and different lignin is used as the raw material for conversion, the highest yield of the aromatic bio-oil is 72%. Raw materials are cheap and wide in source; inorganic acid and alkali are not needed, and generation of a large amount of alkali liquor in traditional lignin catalysis is avoided; the method has the characteristics of cheap tungsten-based catalyst, green reaction process, atom economy and the like, and also has the characteristics of mild reaction conditions, high activity and selectivity, environment-friendly reaction process and the like.
Ruthenium catalyzed synthesis method of primary amine
-
Paragraph 0049-0052, (2020/03/09)
The invention belongs to the field of organic synthesis, and discloses a ruthenium catalyzed synthesis method of primary amine. A ruthenium complex is taken as a catalyst; and a compound (A) and a compound (B) carry out reactions to obtain a compound (C); wherein R1 represents hydrogen or an alkyl group; R2 represents hydrogen or an alkyl group; R3 represent hydrogen, an alkyl group, or a phenyl group; R4 represent one of following structures shown in the description; n represents 0, 1, 2, or 3; R5 represents an alkyl group, an alkoxyl group, an ester group, a phenyl group, or a halogen atom,when n>=2, at least two R5(s) can be identical or different, m represents 0, 1, 2, or 3, R6 represents an alkyl group, an alkoxyl group, an ester group, or a halogen atom, and when m>=2, at least twoR6(s) can be identical or different. The method has the advantages of simple operation, mild conditions, small using amount of catalysts, wide substrate application range, no need of inert gas, and high yield.
