66107-31-1Relevant articles and documents
Zinc chloride-promoted aryl bromide-alkyne cross-coupling reactions at room temperature
Finke, Aaron D.,Elleby, Eric C.,Boyd, Michael J.,Weissman, Haim,Moore, Jeffrey S.
, p. 8897 - 8900 (2009)
(Chemical Equation Presented) Substoichiometric amounts of ZnCl2 promote the room temperature, Pd/P(t-Bu)3-catalyzed cross-coupling of aryl bromides with alkynes. Pd(I) dimer 1 is demonstrated to be a particularly active precatalyst for this reaction. The reaction is general for a wide variety of aryl bromides.
Ligand- and Solvent-Tuned Chemoselective Carbonylation of Bromoaryl Triflates
Shen, Chaoren,Wei, Zhihong,Jiao, Haijun,Wu, Xiao-Feng
supporting information, p. 13369 - 1337 (2017/09/06)
The palladium-catalyzed chemoselective carbonylation of bromoaryl triflates is reported. The selective C?Br bond versus C?OTf (OTf=triflate) bond functionalization can be remarkably tuned by the combination of the ligand [4,5-bis(diphenylphosphino)-9,9-dimethylxanthene (Xantphos) vs. 1,1′-bis(diphenylphosphino)ferrocene (DPPF)] and the solvent (toluene vs. DMSO). The respective ligand and solvent effects are rationalized by DFT calculations. In contrast, the monodentate ligands BuPAd2 and tBu3P prefer the selective C?Br bond activation and are solvent insensitive.
