143824-77-5 Usage
Description
FMOC-ARG(BOC)2-OH, also known as Fmoc-Arginine(Boc)2, is a synthetic compound used in the field of organic chemistry and peptide synthesis. It is a white to off-white powder with specific chemical properties that make it a valuable intermediate in the synthesis of various peptides and proteins.
Uses
Used in Pharmaceutical Industry:
FMOC-ARG(BOC)2-OH is used as an intermediate in membrane-enhanced peptide synthesis for the development of new drugs and therapeutic agents. Its role in peptide synthesis is crucial, as it aids in the formation of complex peptide structures that can be used for various medical applications, including the treatment of diseases and the development of vaccines.
Used in Research and Development:
In the field of research and development, FMOC-ARG(BOC)2-OH is utilized for the synthesis of custom peptides and proteins. This allows scientists to study the structure, function, and interactions of these biomolecules, leading to a better understanding of their roles in biological processes and the potential for new therapeutic strategies.
Used in Chemical Synthesis:
FMOC-ARG(BOC)2-OH is also used in chemical synthesis for the production of various compounds with specific properties. Its versatility as a synthetic intermediate makes it a valuable tool in the development of new materials and chemicals for a wide range of applications, from pharmaceuticals to industrial products.
Check Digit Verification of cas no
The CAS Registry Mumber 143824-77-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,3,8,2 and 4 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 143824-77:
(8*1)+(7*4)+(6*3)+(5*8)+(4*2)+(3*4)+(2*7)+(1*7)=135
135 % 10 = 5
So 143824-77-5 is a valid CAS Registry Number.
InChI:InChI=1/C31H40N4O8/c1-30(2,3)42-28(39)34-26(35-29(40)43-31(4,5)6)32-17-11-16-24(25(36)37)33-27(38)41-18-23-21-14-9-7-12-19(21)20-13-8-10-15-22(20)23/h7-10,12-15,23-24H,11,16-18H2,1-6H3,(H,33,38)(H,36,37)(H2,32,34,35,39,40)/t24-/m0/s1
143824-77-5Relevant articles and documents
Modular Solid-Phase Synthesis of Antiprotozoal Barnesin Derivatives
Roman, Dávid,Ragu?, Luka,Keiff, Fran?ois,Meyer, Florian,Barthels, Fabian,Schirmeister, Tanja,Kloss, Florian,Beemelmanns, Christine
supporting information, p. 3744 - 3748 (2020/04/02)
Here, we applied and optimized a solid support (SP)-based Horner-Wadsworth-Emmons reagent to prepare SP-bound vinylogous amino acids. Subsequent SP-based peptide synthesis, global deprotection, and chemical modifications yielded 14 lipodipeptides carrying
Miraziridine A: Natures blueprint towards protease class-spanning inhibitors
Schaschke, Norbert
, p. 855 - 857 (2007/10/03)
The natural product miraziridine A isolated from the marine sponge Theonella aff. mirabilis unifies within one molecule three structurally privileged elements: (i) (2R,3R)-aziridine-2,3-dicarboxylic acid, (ii) (3S,4S)-4-amino-3-hydroxy-6-methylheptanoic acid (statine), and (iii) (E)-(S)-4-amino-7-guanidino-hept-2-enoic acid (vinylogous arginine). The alignment of them realized in the tetrapetide allows for a simultaneous inhibition of the proteolytic activity of trypsin-like serine proteases, papain-like cysteine proteases, and pepsin-like aspartyl proteases. Therefore, this unique compound represents a blueprint for the design of protease class-spanning inhibitors.
A facile preparation of Fmoc-Argω,ω′(Boc)2 -OH and Z-Argω,ω′ (Boc)2 -OH, new arginine derivatives for peptide synthesis
Verdini, Antonio S.,Lucietto, Pierluigi,Fossati, Gianluca,Giordani, Cristiana
, p. 6541 - 6542 (2007/10/02)
The new arginine derivatives Fmoc-Argω,ω′(Boc)2 -OH and Z-Argω,ω′ (Boc)2 -OH have been easily prepared in hiqh yield starting from Z-Orn-OH and N,N′-bis (tert-butoxycarbonyl) -S-methylisothiourea.
