38654-91-0

Basic information

• Product Name: Benzeneacetic acid, a-(diethoxyphosphinyl)-
• CAS NO: 38654-91-0
• Molecular Formula: C12H17O5P
• Molecular Weight: 272.238
• Mol File: 38654-91-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzeneacetic acid, a-(diethoxyphosphinyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetic acid, a-(diethoxyphosphinyl)-(38654-91-0)
• EPA Substance Registry System: Benzeneacetic acid, a-(diethoxyphosphinyl)-(38654-91-0)

Safety Data

• Hazardous Substances Data: 38654-91-0(Hazardous Substances Data)

Upstream product

• 51863-47-9 (diethoxyphosphoryl)-phenyl-acetic acid methyl ester 
• 37167-62-7 bromo-phenyl-acetic acid methyl ester 
• 59356-28-4 C₁₄H₂₁O₄P 
• 2882-19-1 ethyl 2-phenyl-2-bromoacetate 
• 101-97-3 Ethyl 2-phenylethanoate 
• 31641-78-8 ethyl 2-diethoxyphosphoryl-2-phenylacetate 
• 124-38-9 carbon dioxide 
• 1080-32-6 O,O-diethyl benzylphosphonate 
• 67683-19-6 (diethoxyphosphinyl)phenylketene 

Downstream Products

• 78427-50-6 (E)-2-Phenyl-hex-2-enoic acid 
• 38428-05-6 diethyl ether of α-(N-benzyloxycarbonyl)aminobenzylphosphonic acid 
• 25944-64-3 diethyl (1-phenylethenyl)phosphonate 
• 549546-05-6 C₁₃H₁₂O₄ 
• 33121-49-2 C₁₁H₁₀O₃ 
• 33121-50-5 4-(bromomethyl)-3-phenylfuran-2(5H)-one 
• 1620135-95-6 tert-butyl N-allyl-N-[(2-oxo-3-phenyl-5H-furan-4-yl)methyl]-carbamate 
• 1620135-94-5 tert-butyl N-allyl-N-[(2-oxo-3-phenyl-5H-furan-4-yl)methyl]-carbamate 
• 1620136-11-9 C₂₀H₁₉NO₂ 
• 1620136-12-0 tert-butyl 2-phenylallyl[(3-phenyl-2-oxo-5H-furan-4-yl)-methyl]carbamate 
• 1620136-28-8 3-acetoxy-2-oxopropyl 2-(diethoxyphosphoryl)-2-phenylacetate 
• 108154-66-1 4-(4-nitrophenyl)-3-phenylfuran-2(5H)-one 
• 162011-90-7 rofecoxib 
• 110836-03-8 4-(4'-methoxyphenyl)-3-phenyl-2(5H)-furanone 

Relevant articles and documents

An intramolecular [2 + 2] photocycloaddition approach to conformationally restricted bis-pyrrolidines

With N-Boc-protected 4-(allylaminomethyl)-2(5H)furanones as starting materials, a photochemical approach is presented to give 3,9-diazatricyclo[5.3. 0.01,5]decanes as conformationally restricted bis-pyrrolidines. The products are orthogonally protected at the two nitrogen atoms and exhibit, depending on the substitution pattern at positions C5, C6, and C7, latent C 2 symmetry. When the furanones had a phenyl group at the 3-position (X3), alternative photochemical pathways were observed.

A useful synthesis of diethyl 1-substituted vinylphosphonates

A variety of diethyl 1-substituted vinylphosphonates 8 has been conveniently synthesized by piperidine catalyzed decarboxylative condensation of 2-diethoxyphosphorylalkanoic acids and 2-diethoxyphosphorylalkenoic acids 7 with formaldehyde.

A Facile and General, One-pot Synthesis of 2-Oxoalkane Phosphonates from Diethylphosphonocarboxylic Acid Chlorides and Organometallic Reagents

An efficient and general method for the preparation of 2-oxoalkane phosphonates 2 is described.Diethylphosphono-2-alkanoyl chlorides are used to introduce directly the 2-oxophosphonate 1-substituted synthons on Grignard or cuprate reagents.