69940-70-1

Basic information

• Product Name: C₃₃H₃₄ClN₄O₁₃P
• Synonyms: C₃₃H₃₄ClN₄O₁₃P
• CAS NO: 69940-70-1
• Molecular Weight: 761.079
• Mol File: 69940-70-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₃₃H₃₄ClN₄O₁₃P(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₃H₃₄ClN₄O₁₃P(69940-70-1)
• EPA Substance Registry System: C₃₃H₃₄ClN₄O₁₃P(69940-70-1)

Safety Data

• Hazardous Substances Data: 69940-70-1(Hazardous Substances Data)

Upstream product

• 15074-54-1 2-chlorophenyl dichlorophosphate 
• 50-89-5 thymidine 
• 40615-39-2 5'-O-(4-4'-dimethoxytrityl)thymidine 
• 17331-53-2 3'-O-benzoylthymidine 
• 76958-58-2 [1,2,4]Triazol-1-yl-phosphonic acid (2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester 2-chloro-phenyl ester 
• 93966-64-4 3'-benzoyl-5'-O-(4,4'-dimethoxytrityl)thymidine 
• 98-88-4 benzoyl chloride 
• 72351-28-1 2-chlorophenyl phosphordi(1H-1-[1,2,4]triazolide) 
• 80817-37-4 5'-O-(dimethoxytrityl)thymidine 3'-(o-chlorophenyl β-cyanoethyl phosphate) 
• 81196-20-5 2-chlorophenyl 5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl phosphate 
• 81187-04-4 C₅₄H₅₂ClN₄O₁₅P 

Relevant articles and documents

Simplified Liquid-Phase Preparation of Four Decadeoxyribonucleotides and their Preliminary Spectroscopic Characterization

Four self-complementary decadeoxyribonucleotides, dApTpApTpApTpApTpApT,dApTpApTpCpGpApTpApT, dApTpApTpGpCpApTpApT and dApApApApApTpTpTpTpT, were chemically synthesized by the phosphotriester procedure.Efforts were concentrated on keeping the procedure as simple as possible, concomitant with obtaining high-purity products at each step of the process.The decamers were elaborated from the 3'-end, starting with a 3'-O-benzoylated monomer according to the scheme: monomer + monomer -> dimer + dimer -> tetramer + dimer -> hexamer + tetramer -> decamer.Putity of intermediates and of the fully blocked decamers were monitored by chromatography and by 300-MHz 1H-NMR. spectroscopy.The deblocked decadeoxyribonucleotides were characterized by their UV., CD., and 1H-NMR. spectra.