DL-Methamphetamine

Base Information

• Chemical Name: DL-Methamphetamine
• CAS No.: 7632-10-2
• Deprecated CAS: 4846-07-5,30639-16-8
• Molecular Formula: C10H15N
• Molecular Weight: 149.236
• European Community (EC) Number: 231-559-0,225-433-4
• NSC Number: 403767
• UNII: 13ZT6YG5SD
• DSSTox Substance ID: DTXSID3043861
• Nikkaji Number: J8.954K
• Wikidata: Q44909815
• NCI Thesaurus Code: C90834
• ChEMBL ID: CHEMBL508
• Mol file: 7632-10-2.mol

Synonyms:Deoxyephedrine;Desoxyephedrine;Desoxyn;Hydrochloride, Methamphetamine;Madrine;Metamfetamine;Methamphetamine;Methamphetamine Hydrochloride;Methylamphetamine;N Methylamphetamine;N-Methylamphetamine

 This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.

Chemical Property of DL-Methamphetamine

Chemical Property:

• Melting Point: 134-135 °C
• Refractive Index: 1.5620 (estimate)
• Boiling Point: 215.5°Cat760mmHg
• PKA: 10.38±0.10(Predicted)
• Flash Point: 86.8°C
• PSA: 12.03000
• Density: 0.907g/cm³
• LogP: 2.22790
• Storage Temp.: -20°C
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 149.120449483
• Heavy Atom Count: 11
• Complexity: 95

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(CC1=CC=CC=C1)NC

Technology Process of DL-Methamphetamine

There total 61 articles about DL-Methamphetamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methyl-(1-methyl-2-phenyl-ethyliden)-amine (29686-21-3,75029-56-0) → methamphetamin (7632-10-2)

Guidance literature:

With 2-[bis(pentafluorophenyl)boryl]-N,N-dimethylaniline; In benzene-d6; at 80 ℃; for 22h; under 1500.15 Torr; Inert atmosphere;

DOI:10.1039/c2dt30926b

Reference yield: 69.0%

methylamine hydrochloride (593-51-1) + 1-phenyl-acetone (103-79-7,136675-26-8) → methamphetamin (7632-10-2) + 2,6-dimethyl-3,5-diphenylpyridine (65907-81-5) + 3-phenyl-2-propanol (698-87-3,14898-87-4) + N-benzoylmethamphetamine (73355-87-0) + N-(1-methyl-2-phenylethyl)benzamide (70631-05-9,1795-95-5) + N-acetylmethamphetamine (27765-80-6) + N-formylmethamphetamine (42932-20-7,26343-75-9,894793-16-9) + N-(β-phenylisopropyl)benzyl(methyl)ketimine (74917-80-9) + 2-amino-1-phenylpropane (60-15-1,156-34-3,51-64-9,300-62-9,17108-96-2,96332-84-2) + 3,4-diphenylbut-3-en-2-one (1722-69-6)

Guidance literature:

With aluminum amalgam; sodium hydroxide; In methanol; at -10 - 60 ℃; for 1.5h;

DOI:10.1021/ac9005588

Reference yield: 60.0%

allylbenzene (300-57-2,57807-91-7) + methylamine (74-89-5) → methamphetamin (7632-10-2)

Guidance literature:

With n-butyllithium; at 50 ℃;

DOI:10.1002/1615-4169(200209)344:8<795::AID-ADSC795>3.0.CO;2-Q

upstream raw materials:

formaldehyd

2-amino-1-phenylpropane

4-methyl-5-phenyl-1,3-thiazole

sodium ethanolate

Downstream raw materials:

Methamphetamin

(R)-2-methylamino-1-phenylpropane

propylhexedrine

p-nitromethamphetamine

Refernces

• 1、 -. "DEUTERIUM FREE, STABLE ISOTOPE LABELED 2-PHENYLETHYLAMINE HALLUCINOGENS AND/OR STIMULANTS, METHODS OF THEIR PREPARATION AND THEIR USE". Page/Page column. . Retrieved 2014/08/19.
• 2、 Sumerin, Victor,Chernichenko, Konstantin,Nieger, Martin,Leskelae, Markku,Rieger, Bernhard,Repo, Timo. "Highly active metal-free catalysts for hydrogenation of unsaturated nitrogen-containing compounds". experimental part. p. 2093 - 2110. Retrieved 2011/11/06.